Obfuscated mobile malware (OMM) is a malicious software in mobile that hides to avoid detection and annihilation. These types of malwares are thorny to identify due to their inevitable nature. Deep learning (DL) algorithms are the most desirable to detect obfuscated malware based on the ‘n’ number of iterations with adjustable weights and neurons. This study investigates the accurate detection of OMM using significant DL algorithms such as multi-layer perceptron (MLP), self-organizing maps (SOM), long short-term memory (LSTM) networks, auto encoders (AE), and convolutional neural network (CNN) based on appropriate parameter tuning. The dataset taken for the study is CICMalMem2022 that contains 58,596 samples with 57 features which is basically designed for OMM detection. The dataset comprises Spyware, Ransomware, Trojan horse, and Benign. The DL models are evaluated based on performance metrics such as precision, recall, accuracy, training accuracy, test accuracy, validation accuracy, training loss, validation loss and receiver operating characteristic (ROC) curve. Based on the experimental evaluation, the study reveals that LSTM outperforms with 100% accuracy and MLP achieves 99.9% accuracy in detecting and classifying the OMM using deep supervised learning (SL) mechanism.