Limited understanding exists regarding the methodologies behind designing interfaces for low-income contexts, despite acknowledging their potential value. The ERSA (Engineering design Research meta-model based Systematic Analysis) process, defined as a dynamic interactive multi-process system, proposes a new approach to constructing learnings to succeed in designing interfaces for low-income countries. ERSA is developed by integrating database searches, snowballing, thematic similarity searches for corpus of literature creation, multilayer networks, clustering algorithms, and data processing. ERSA employs an engineering design meta-model to analyze the corpus of literature, facilitating the identification of diverse methodological approaches. The insights from ERSA empower researchers, designers, and engineers to tailor design methodologies to their specific low-income contexts. Our findings show the importance of adopting more versatile and holistic approaches. They suggest that user-based design methodologies and computational design can be defined and theorized together.