Intelligent recognition of colorectal cancer combining application of computer-assisted diagnosis with deep learning approaches

Human colorectal disorders in the digestive tract are recognized by reference colonoscopy. The current system recognizes cancer through a three-stage system that utilizes two sets of colonoscopy data. However, identifying polyps by visualization has not been addressed. The proposed system is a five-stage system called ColoRectalCADx, which provides three publicly accessible datasets as input data for cancer detection. The three main datasets are CVC Clinic DB, Kvasir2, and Hyper Kvasir. After the image preprocessing stages, system experiments were performed with the seven prominent convolutional neural networks (CNNs) (end-to-end) and nine fusion CNN models to extract the spatial features. Afterwards, the end-to-end CNN and fusion features are executed. These features are derived from Discrete Wavelet Transform (DWT) and Vector Support Machine (SVM) classification, that was used to retrieve time and spatial frequency features. Experimentally, the results were obtained for five stages. For each of the three datasets, from stage 1 to stage 3, end-to-end CNN, DenseNet-201 obtained the best testing accuracy (98%, 87%, 84%), ((98%, 97%), (87%, 87%), (84%, 84%)), ((99.03%, 99%), (88.45%, 88%), (83.61%, 84%)). For each of the three datasets, from stage 2, CNN DaRD-22 fusion obtained the optimal test accuracy ((93%, 97%) (82%, 84%), (69%, 57%)). And for stage 4, ADaRDEV2-22 fusion achieved the best test accuracy ((95.73%, 94%), (81.20%, 81%), (72.56%, 58%)). For the input image segmentation datasets CVC Clinc-Seg, KvasirSeg, and Hyper Kvasir, malignant polyps were identified with the UNet CNN model. Here, the loss score datasets (CVC clinic DB was 0.7842, Kvasir2 was 0.6977, and Hyper Kvasir was 0.6910) were obtained.

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“…Flow diagram: the flow diagram for the proposed ColoRectalCADx [ 28 , 29 ] system with the explanation of each stage is shown in Figure 1 .…”

Section: Methodsmentioning

confidence: 99%

Dexterous Identification of Carcinoma through ColoRectalCADx with Dichotomous Fusion CNN and UNet Semantic Segmentation

Raju

Jayavel

Rajalakshmi

2022

Computational Intelligence and Neuroscience

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“…Colorectal cancer (CRC) ranks third among the most frequently diagnosed illnesses in both men and women [1]. According to projections published by the American Cancer Society, the United States is expected to witness 46,050 newly diagnosed cases of rectal cancer and 106,970 newly diagnosed cases of colon cancer in 2023.…”

Section: Introductionmentioning

confidence: 99%

A deep learning framework for accurate diagnosis of colorectal cancer using histological images

Attia,

F. Areed,

Amer

et al. 2024

IJECE

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Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide, with high mortality and incidence rates. Early detection of the disease may increase the probability of survival, making it critical to develop effective procedures for precise treatment. In the past few years, there has been an increased use of deep learning techniques in image classification that aid in the detection of various types of cancer. In this study, convolutional neural network (CNN) models were used to classify colorectal cancer into benign and malignant. After applying various data preprocessing techniques to the image dataset, we evaluated our prototypes using three distinct subsets of testing data, representing 20%, 30%, and 40% of the total dataset. Additionally, four pre-trained CNN models (ResNet-18, ResNet-50, GoogLeNet, and MobileNetV2) were trained, and the network architectural techniques were compared by applying the Adam optimizer. Finally, we assessed the performance of algorithms in terms of accuracy, sensitivity, specificity, precision, F1-score, and area under the receiver operating characteristic (ROC) curve (AUC). In this research, deep learning approaches demonstrated high efficacy in accurately diagnosing colorectal cancer. This indicates that these techniques have an important and significant value for advancing medical research.

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ColoRectalCADx: Expeditious Recognition of Colorectal Cancer with Integrated Convolutional Neural Networks and Visual Explanations Using Mixed Dataset Evidence

Raju

Jayavel

Rajalakshmi

2022

Computational and Mathematical Methods in Medicine

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Colorectal cancer typically affects the gastrointestinal tract within the human body. Colonoscopy is one of the most accurate methods of detecting cancer. The current system facilitates the identification of cancer by computer-assisted diagnosis (CADx) systems with a limited number of deep learning methods. It does not imply the depiction of mixed datasets for the functioning of the system. The proposed system, called ColoRectalCADx, is supported by deep learning (DL) models suitable for cancer research. The CADx system comprises five stages: convolutional neural networks (CNN), support vector machine (SVM), long short-term memory (LSTM), visual explanation such as gradient-weighted class activation mapping (Grad-CAM), and semantic segmentation phases. Here, the key components of the CADx system are equipped with 9 individual and 12 integrated CNNs, implying that the system consists mainly of investigational experiments with a total of 21 CNNs. In the subsequent phase, the CADx has a combination of CNNs of concatenated transfer learning functions associated with the machine SVM classification. Additional classification is applied to ensure effective transfer of results from CNN to LSTM. The system is mainly made up of a combination of CVC Clinic DB, Kvasir2, and Hyper Kvasir input as a mixed dataset. After CNN and LSTM, in advanced stage, malignancies are detected by using a better polyp recognition technique with Grad-CAM and semantic segmentation using U-Net. CADx results have been stored on Google Cloud for record retention. In these experiments, among all the CNNs, the individual CNN DenseNet-201 (87.1% training and 84.7% testing accuracies) and the integrated CNN ADaDR-22 (84.61% training and 82.17% testing accuracies) were the most efficient for cancer detection with the CNN+LSTM model. ColoRectalCADx accurately identifies cancer through individual CNN DesnseNet-201 and integrated CNN ADaDR-22. In Grad-CAM’s visual explanations, CNN DenseNet-201 displays precise visualization of polyps, and CNN U-Net provides precise malignant polyps.

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Intelligent recognition of colorectal cancer combining application of computer-assisted diagnosis with deep learning approaches

Cited by 3 publications

References 21 publications

Dexterous Identification of Carcinoma through ColoRectalCADx with Dichotomous Fusion CNN and UNet Semantic Segmentation

Dexterous Identification of Carcinoma through ColoRectalCADx with Dichotomous Fusion CNN and UNet Semantic Segmentation

A deep learning framework for accurate diagnosis of colorectal cancer using histological images

ColoRectalCADx: Expeditious Recognition of Colorectal Cancer with Integrated Convolutional Neural Networks and Visual Explanations Using Mixed Dataset Evidence

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