Intensity Dependent Effects of Interval Resistance Training on Myokines and Cardiovascular Risk Factors in Males With Obesity

Ataeinosrat, Ali; Saeidi, Ayoub; Abednatanzi, Hossein; Rahmani, Hiwa; Daloii, Asieh Abbassi; Pashaei, Zhaleh; Hojati, Vida; Basati, Gholam; Mossayebi, Ali; Laher, Ismail; Alesi, Michaela G.; Hackney, Anthony C.; VanDusseldorp, Trisha A.; Zouhal, Hassane

doi:10.3389/fendo.2022.895512

Cited by 12 publications

(6 citation statements)

References 71 publications

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“…In this regard, Nasiri et al reported that eight weeks of Pilates training had no significant impact on serum DCN (24). Ataeinosrat et al also concluded that low-intensity resistance training had no influence on serum DCN, but moderate and high-intensity training increased it in rats (25).…”

Section: Discussionmentioning

confidence: 99%

Effect of aerobic and resistance training on secreted protein acidic rich in cysteine, decorin, and myonectin muscle genes expression in rats fed with a high-fat diet

Babaeinejad,

Matinhomaee,

Fatolahi

2023

J Shahrekord Univ Med Sci

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Background and aims: Fatty diet can affect the expression of myokines. Thus, the aim of this study was to evaluate the effect of aerobic and resistance training secreted protein acidic rich in cysteine (SPARC), decorin (DCN), and myonectin muscle gene expression in rats fed with a high-fat diet. Methods: In this experimental study, 32 rats were randomly divided into healthy control, obese control, obese+aerobic exercise, and obese+resistance exercise groups. The training program was implemented for 4 weeks at aerobic moderate intensity (50% VO2max in the first week and 65% VO2max in the last week). For resistance training, the animals were also trained to climb the ladder (height 110 cm, slope 80%, and the distance between the bars of the ladder 2 cm), which is based on the determination of one-repetition maximum (1RM). Obese rats received a dose of 0.5 mL/100 g of body weight orally by gavage for 4 weeks and 5 days a week. Results: There was no significant difference between the groups in terms of DCN expressions (P=0.702). However, the expression of SPARC (P=0.039) and myonectin in the obese control group was significantly increased compared to the healthy control (P=0.038). The expression of SPARC and myonectin in the aerobic training group (P=0.038, P=0.042) and the resistance training group (P=0.048, P=0.049) was significantly decreased in comparison to obesity control. Resistance training caused a greater decrease in myonectin compared to aerobic training (P=0.049). Conclusion: The findings revealed that aerobic and resistance exercises are effective in reducing SPARC and myonectin expression in the skeletal muscle of rats fed with a high-fat diet.

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Section: Discussionmentioning

confidence: 99%

Effect of aerobic and resistance training on secreted protein acidic rich in cysteine, decorin, and myonectin muscle genes expression in rats fed with a high-fat diet

Babaeinejad,

Matinhomaee,

Fatolahi

2023

J Shahrekord Univ Med Sci

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“…After collection, the tubes were gently shaken five times for thorough mixing, and then the samples were placed on ice and refrigerated. After collecting blood from all participants, the blood collection tubes were centrifuged at 3000 r/min and 4 °C for 10 min to separate the plasma 26 . The Architect C-8000 (Abbott Laboratories, USA) automated chemistry analyzer was utilized to measure total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), alanine aminotransferase (ALT), and uric acid (UA) 27 .…”

Section: Methodsmentioning

confidence: 99%

Comparative effects of high-intensity interval training and moderate-intensity continuous training on weight and metabolic health in college students with obesity

Song,

Cui,

et al. 2024

Sci Rep

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The purpose of this study was to compare the effects of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) on weight, body composition, blood lipid indicators, and metabolic status in college students living with obesity. The study focused on a sample of 40 college students living with obesity, including 20 males and 20 females, aged between 18 and 25. Participants were randomly assigned to either the HIIT group or the MICT group. Both groups underwent an 8-week intervention, consisting of three sessions per week with alternate-day training. The MICT group's training consisted of continuous aerobic exercise for 35 min at 60–70% of maximum heart rate. The HIIT group engaged in 28 min of alternating high-intensity and low-intensity exercise, where the high-intensity phase was at 85–90% of maximum heart rate for 4 min, followed by a 3-min recovery period at 50–60% of maximum heart rate, repeated four times. Both groups underwent heart rate monitoring before and after the training sessions to ensure the accuracy of the training intensity. Within each group, further distinctions were made based on gender, resulting in the following subgroups: Male HIIT group (n = 10), Female HIIT group (n = 10), Male MICT group (n = 10), and Female MICT group (n = 10). Differences in anthropometric and biochemical indicators among the groups were analyzed, and the different effects of the two intervention strategies on the obese college student population were comprehensively evaluated. Compared to the baseline assessment, the HIIT group showed a more favorable declining trend than the MICT group in terms of body morphology and body composition, particularly in the aspect of body fat percentage (BF%). The male HIIT group, female HIIT group, male MICT group, and female MICT group respectively reduced by − 23.71%, − 26.76%, − 9.81%, − 7.16%. Male and female HIIT group experienced a more pronounced decrease compared to the MICT group, with the female HIIT group reducing an additional 3.75% more than the male HIIT group. Regarding intergroup differences, BF% significant differences were shown between male MICT group and the HIIT group (P < 0.05), and female MICT group and the HIIT group (P < 0.01). In terms of biochemical indicators, the HIIT group also presented a more favorable declining trend compared to the MICT group, with male HIIT participants showing more reduction than female HIIT participants, especially in total cholesterol (TC) (10.64%), low-density lipoprotein cholesterol (LDL-C) (11.73%), alanine aminotransferase (ALT) (11.99%), and uric acid (UA) (11.76%). Regarding triglycerides (TG), significant intergroup differences were observed between male MICT and HIIT groups (P < 0.01) and female MICT and HIIT groups (P < 0.01). Concerning ALT, a significant difference was shown between female MICT and HIIT groups (P < 0.01), while no significant difference was observed among male participants. Overall, for college students living with obesity, both HIIT and MICT have shown positive effects. Among these, HIIT demonstrates greater effectiveness compared to MICT in BF% and biochemical markers.

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Section: Can Exerkines (Generated/stimulated By Physical Activity/phy...mentioning

confidence: 99%

“…A study found low-intensity interval resistance training can lead to beneficial changes in myokines [ 65 ]. In this study, subjects performed resistance training for 12 weeks, with 40% 1RM and 15 to 20 repetitions [ 65 ]. However, low-intensity physical exercise of 20–40 Vo 2max or 35–45% of HR max , such as running, cycling, or walking, for less than five weeks appears not to affect myokines [ 30 , 31 , 32 , 34 ].…”

Section: Can Exerkines (Generated/stimulated By Physical Activity/phy...mentioning

confidence: 99%

The Potential of Exerkines in Women’s COVID-19: A New Idea for a Better and More Accurate Understanding of the Mechanisms behind Physical Exercise

Hekmatikar

Jalalian

Abbasi

et al. 2022

IJERPH

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The benefits of physical exercise are well-known, but there are still many questions regarding COVID-19. Chow et al.’s 2022 study, titled Exerkines and Disease, showed that a special focus on exerkines can help to better understand the underlying mechanisms of physical exercise and disease. Exerkines are a group of promising molecules that may underlie the beneficial effects of physical exercise in diseases. The idea of exerkines is to understand the effects of physical exercise on diseases better. Exerkines have a high potential for the treatment of diseases and, considering that, there is still no study of the importance of exerkines on the most dangerous disease in the world in recent years, COVID-19. This raises the fundamental question of whether exerkines have the potential to manage COVID-19. Most of the studies focused on the general changes in physical exercise in patients with COVID-19, both during the illness and after discharge from the hospital, and did not investigate the basic differences. A unique look at the management of COVID-19 by exerkines, especially in obese and overweight women who experience high severity of COVID-19 and whose recovery period is long after discharge from the hospital, can help to understand the basic mechanisms. In this review, we explore the potential of exerkines in COVID-19 by practicing physical exercise to provide compelling practice recommendations with new insights.

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Intensity Dependent Effects of Interval Resistance Training on Myokines and Cardiovascular Risk Factors in Males With Obesity

Cited by 12 publications

References 71 publications

Effect of aerobic and resistance training on secreted protein acidic rich in cysteine, decorin, and myonectin muscle genes expression in rats fed with a high-fat diet

Effect of aerobic and resistance training on secreted protein acidic rich in cysteine, decorin, and myonectin muscle genes expression in rats fed with a high-fat diet

Comparative effects of high-intensity interval training and moderate-intensity continuous training on weight and metabolic health in college students with obesity

The Potential of Exerkines in Women’s COVID-19: A New Idea for a Better and More Accurate Understanding of the Mechanisms behind Physical Exercise

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