Intensity modulated radiotherapy (IMRT) the white, black and grey: a clinical perspective

Joseph, Bindhu; Supe, Sanjay S.; Pawar, Y. S.

doi:10.1016/s1507-1367(10)60101-0

Cited by 16 publications

(9 citation statements)

References 35 publications

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“…[31][32][33][34] Reduction of acute reaction intensity is observed which, in turn, largely affects patients quality of life. 33,35,36 Data published and own results confirm that IMRT allows to decrease dose to critical organs, especially to the lungs. [37][38][39] We have observed that maximal and medium dose in the heart and the lung and V20 in the lung on the irradiated side and V20 evaluated for both lungs were lower for IMRT than for 3D tangential beams.…”

Section: Discussionmentioning

confidence: 69%

Comparison between intensity modulated radiotherapy (IMRT) and 3D tangential beams technique used in patients with early-stage breast cancer who received breast-conserving therapy

Sas-Korczyńska

Śladowska

Rozwadowska-Bogusz

et al. 2010

Reports of Practical Oncology & Radiotherapy

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Section: Discussionmentioning

confidence: 69%

Comparison between intensity modulated radiotherapy (IMRT) and 3D tangential beams technique used in patients with early-stage breast cancer who received breast-conserving therapy

Sas-Korczyńska

Śladowska

Rozwadowska-Bogusz

et al. 2010

Reports of Practical Oncology & Radiotherapy

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“…The use of the MLC allows for both static modulation of a treatment field, which remains fixed during the emission of ionizing radiation [4, 5], and for dynamic modulation, causing changes in the shape of the field in the course of radiation emission [6]. The latter solution enables the delivery of intensity-modulated radiotherapy (IMRT) [7–9]. …”

Section: Introductionmentioning

confidence: 99%

Tomotherapy – a different way of dose delivery in radiotherapy

Piotrowski¹,

Skórska²,

Jodda³

et al. 2012

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Aim of the studyHelical tomotherapy is one of the methods of radiotherapy. This method enables treatment implementation for a wide spectrum of clinical cases. The vast array of therapeutic uses of helical tomotherapy results directly from the method of dose delivery, which is significantly different from the classic method developed for conventional linear accelerators. The paper discusses the method of dose delivery by a tomotherapy machine. Moreover, an analysis and presentation of treatment plans was performed in order to show the therapeutic possibilities of the applied technology. Dose distributions were obtained for anaplastic medulloblastoma, multifocal metastases to brain, vulva cancer, tongue cancer, metastases to bones, and advanced skin cancer. Tomotherapy treatment plans were compared with conventional linear accelerator plans.ResultsFollowing the comparative analysis of tomotherapy and conventional linear accelerator plans, in each case we obtained the increase in dose distribution conformity manifested in greater homogeneity of doses in the radiation target area for anaplastic medulloblastoma, multifocal metastases to brain, vulva cancer, metastases to bones, and advanced skin cancer, and the reduction of doses in organs at risk (OAR) for anaplastic medulloblastoma, vulva cancer, tongue cancer, and advanced skin cancer. The time of treatment delivery in the case of a tomotherapy machine is comparable to the implementation of the plan prepared in intensity-modulated radiotherapy (IMRT) technique for a conventional linear accelerator. In the case of tomotherapy the application of a fractional dose was carried out in each case during one working period of the machine. For a conventional linear accelerator the total value of the fractional dose in the case of anaplastic medulloblastoma and metastases to bones was delivered using several treatment plans, for which a change of set-up was necessary during a fraction.ConclusionThe obtained results confirm that tomotherapy offers the possibility to obtain precise treatment plans together with the simplification of the therapeutic system.

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“…[5][6][7][8] Through intensity modulated radiation therapy (IMRT), it has became possible to provide a relatively safe treatment with doses to prostate above 70 Gy and comparable doses for adjacent organs at risk (OAR) (bladder and rectum) as for 3D technique. 9 In recent years, the high conformal techniques like Tomotherapy or CyberKnife has become available. With these techniques, it is possible to obtain a larger dose-decrease gradient outside the target, so dose escalation has become even safer.…”

Section: Introductionmentioning

confidence: 99%

Comparison of dose volume histograms for supine and prone position in patients irradiated for prostate cancer—A preliminary study

Bajon

Piotrowski

Antczak

et al. 2011

Reports of Practical Oncology & Radiotherapy

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Intensity modulated radiotherapy (IMRT) the white, black and grey: a clinical perspective

Cited by 16 publications

References 35 publications

Comparison between intensity modulated radiotherapy (IMRT) and 3D tangential beams technique used in patients with early-stage breast cancer who received breast-conserving therapy

Comparison between intensity modulated radiotherapy (IMRT) and 3D tangential beams technique used in patients with early-stage breast cancer who received breast-conserving therapy

Tomotherapy – a different way of dose delivery in radiotherapy

Comparison of dose volume histograms for supine and prone position in patients irradiated for prostate cancer—A preliminary study

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