Intensive care management of a patient with necrotizing fasciitis due to non-O1/O139 Vibrio cholerae after traveling to Taiwan: a case report

Abstract

Background: Vibrio cholerae are oxidase-positive bacteria that are classified into various serotypes based on the O surface antigen. V. cholerae serotypes are divided into two main groups: the O1 and O139 group and the non-O1/ non-O139 group. O1 and O139 V. cholerae are related to cholera infection, whereas non-O1/non-O139 V. cholerae (NOVC) can cause cholera-like diarrhea. A PubMed search revealed that only 16 cases of necrotizing fasciitis caused by NOVC have been recorded in the scientific literature to date. We report the case of a Japanese woman who developed necrotizing fasciitis caused by NOVC after traveling to Taiwan and returning to Japan. Case presentation: A 63-year-old woman visited our hospital because she had experienced left knee pain for the past 3 days. She had a history of colon cancer (Stage IV: T3N3 M1a) and had received chemotherapy. She had visited Taiwan 5 days previously, where she had received a massage. She was diagnosed with septic shock owing to necrotizing fasciitis. She underwent fasciotomy and received intensive care. She recovered from the septic shock; however, after 3 weeks, she required an above-knee amputation for necrosis and infection. Her condition improved, and she was discharged after 22 weeks in the hospital. Conclusions: With the increase in tourism, it is important for clinicians to check patients' travel history. Clinicians should be alert to the possibility of necrotizing fasciitis in patients with risk factors. Necrotizing fasciitis caused by NOVC is severe and requires early fasciotomy and debridement followed by intensive postoperative care.

Atypische bakterielle Infektionen an der Hand

“…⅔ der Fälle eine umschriebene Phlegmone, mit oder ohne Blasenbildung und hämorrhagischen Läsionen. Seltener (29,2 %) tritt eine nekrotisierende Fasziitis auf 30 . Bei bis 2015 publizierten 48 Fällen errechneten Maraki u. Mitarb.…”

Atypische bakterielle Infektionen an der Hand

“…⅔ der Fälle eine umschriebene Phlegmone, mit oder ohne Blasenbildung und hämorrhagischen Läsionen. Seltener (29,2 %) tritt eine nekrotisierende Fasziitis auf [30]. Bei bis 2015 publizierten 48 Fällen errechneten Maraki und Mitarb.…”

Whole Genome Analysis of a Non-O1, Non-O139 Vibrio cholerae Detected from Human Blood in China

“…15 Tsuruta et al detected NOVC from blood cultures of patients undergoing chemotherapy. 16 The patient had no clear epidemiological history and the cause of infection was unknown. The patient later developed a severe lung infection, which could not be ruled out as being caused by the NOVC strain.…”