Intensive Care of a Weil’s Disease With Multiorgan Failure

Toğal, Türkan; Şener, Ali; Yücel, Neslihan; Demirbilek, Semra; Akgün, Feride Sinem; Aydoğan, Mustafa Said; Uçar, Muharrem; Ersoy, M. Özcan

doi:10.4021/jocmr2010.05.302w

Cited by 13 publications

(10 citation statements)

References 10 publications

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“…A score between 20 and 25 suggests leptospirosis as a possible diagnosis and this patient showed a strong presumption of the disease with a diagnostic score of 32 similarly same recommendations are followed in the intensive case report with multiorgan failure by Turkam Togal study. 12 The presence of acute kidney injury in this case might be due to various factors like direct nephrotoxicity, hypovolemia, acute tubular necrosis, rhabdomyolysis and endotoxin associated vasoconstriction. Neurological involvement occurred on third day of hospitalisation where patient experienced involuntary jerky movements and are considered to be likely tremors due to fever.…”

Section: Discussionmentioning

confidence: 81%

Weil’s Disease With a Pathognomonic Conjunctival Suffusion and Rashes: A Case Report

K¹,

Channaraya²,

Prudhivi³

et al. 2019

Int. J. Res. Ayurveda Pharm.

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Leptospirosis is an emerging infectious disease, as illustrated by recent large outbreaks in Asia, Central and South America, and the United States. Severe form of leptospirosis, characterized by jaundice, renal dysfunction, and haemorrhagic diathesis, is referred to as Weil's disease. The outbreak of Weil's disease in India has increased in past couple of years due to worst floods. A 39year old male admitted to the hospital with fever, uniform rashes, chills, and weakness. Initially the dengue and malaria rapid tests were negative with elevated GRBS, serum creatinine, bilirubin levels, SGOT/SGPT and decreased platelets. Patient was put on antibiotics in view of sepsis with UTI, AKI and thrombocytopenia. The next day Leptospirosis was confirmed with leptospira IgM and ELISA. The patient developed conjunctival suffusion, jerky movements and pedal oedema during hospitalisation which was decreased within 2days with the antibiotics. The hepatic and renal function improved on 6 th day of admission and slowly the patient improved biochemically and symptomatically. The patient recovered and discharged after 9days of hospitalisation. The above case of Weil's disease presented was initially misinterpreted as Dengue this should serve to alert healthcare providers and the general public as leptospirosis is often overlooked and under diagnosed due to its non-specific symptoms. The physicians should be alerted to consider leptospirosis in the differential diagnosis so that early empirical treatment can be given.

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Section: Discussionmentioning

confidence: 81%

Weil’s Disease With a Pathognomonic Conjunctival Suffusion and Rashes: A Case Report

K¹,

Channaraya²,

Prudhivi³

et al. 2019

Int. J. Res. Ayurveda Pharm.

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“…Leptospirosis is a spirochete interrogatory Leptospira's zoonosis. In tropical and subtropical areas, this disease is significantly higher compared to temperate regions [1].…”

Section: Introductionmentioning

confidence: 95%

Leptospirosis Case Report with Renal Insufficiency

Pohekar

Singh

2021

JPRI

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Introduction: Leptospirosis is an international zoonotic condition relay and rising prevalencethe causes of the infection Leptospira spirochete with popular exhibition of polluted clean water.Most asymptomatic diseases, but the symptoms are moderate, autonomous, specific febrile and respiratory non-specific disorder high mortality rates of renal failure. Case: A 33-years-old woman from rural area came to the hospital in casualty with a history of high grade fever (40 degree Celsius), with chilling, headache, stiff neck. Urinary retention along with productive cough for three days. Intervention: The patient underwent inpatient management, which included tablet Ceftriaxone 1gm twice a day, Tablet Doxycycline 100 mg bd given and intravenous fluids 5% dextrose and dextrose/sodium chloride solution, Injection Furosemide20 mg intravenously twice a day were given to the patients. Nursing management: monitoring the vital sign, maintain the O2 levels as well as the consumption and output. All basic nursing care has been provided. Her symptoms cured after two weeks of treatment, she was discharged. Results: Fever has been minimized. The therapy is reacted to and restored. Conclusion: Management was mainly aimed at protecting patient wellbeing, preventing complications and improving the quality of life. The patient received all medical therapy and the results show that the therapy and care was effective.

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“…Leptospirosis is a widespread zoonotic disease caused by a pathogenic spirochete called Leptospira. This zoonosis disease is common in tropical and subtropical regions, where it significantly increases morbidity and mortality ( 1 , 2 ). Leptospiral infection is transmitted to humans by infected animals, including rodents, cats, and dogs.…”

Section: Introductionmentioning

confidence: 99%

Case report: Leptospirosis with multi-organ failure complicated by massive upper gastrointestinal bleeding in a non-epidemic setting with successful management

Thalji

Qunibi²,

Muhtasib³

et al. 2023

Front. Surg.

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Leptospirosis is a common zoonotic disease with a wide range of clinical manifestations, specifically in tropical regions. Weil's disease is considered a severe form of leptospirosis seen in a minority of leptospirosis cases with considerable mortality. These patients typically developed the triad of acute renal injury, jaundice, and hemorrhages. Herein, we reported a case of a 28-year-old male transferred to our intensive care unit due to severe leptospirosis with diffuse alveolar hemorrhage, cholestatic jaundice, acute respiratory distress, and renal injury. The patient was successfully managed with appropriate antimicrobial treatment and other supportive management, including mechanical ventilation, vasopressor, and corticosteroid therapy. Ten days after admission, the patient unexpectedly developed uncontrollable massive upper gastrointestinal bleeding, requiring immediate surgical interventions. Splenectomy, partial gastrectomy, along with gastro-esophageal anastomosis were performed. Following a prolonged hospitalization, the patient fully recovered and was discharged home with excellent clinical outcomes. This fulminant leptospirosis case described here should assist in informing medical professionals of the clinical significance of this serious, occasionally fatal illness. Moreover, leptospirosis should be considered in any location wherever risk factors are present, not just in epidemic and tropical areas. In this case, we pointed out that serious complications of leptospirosis, such as hemorrhage, may happen despite their rarity. In such cases, adopting an integrated multidisciplinary team approach is essential to prevent complications and reduce mortality.

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Intensive Care of a Weil’s Disease With Multiorgan Failure

Cited by 13 publications

References 10 publications

Weil’s Disease With a Pathognomonic Conjunctival Suffusion and Rashes: A Case Report

Weil’s Disease With a Pathognomonic Conjunctival Suffusion and Rashes: A Case Report

Leptospirosis Case Report with Renal Insufficiency

Case report: Leptospirosis with multi-organ failure complicated by massive upper gastrointestinal bleeding in a non-epidemic setting with successful management

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