Intensive Care of Small Premature Infants

Vapaavuori, Eero K.; Krohn, Kai

doi:10.1111/j.1651-2227.1971.tb06617.x

Cited by 9 publications

(4 citation statements)

References 25 publications

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“…Consequently continued follow-up studies are in progress. At the present time our results are similar to those reported by other neonatal units after intensive care of very low birth weight infants showing an incidence of neurological handicaps varying between 9.5 and 25% (3, 5, 16,23,27). Still it must be realized that comparisons between different materials are difficult as many variables often differ, e.g.…”

Section: Outcomesupporting

confidence: 90%

Respiratory Insufficiency Syndrome (Ris) in Preterm Infants With Gestational Age of 32 Weeks and Less

Carlsson¹,

Svenningsen²

1976

Obstetrical & Gynecological Survey

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Carlsson, J. and Svenningsen, N. W. (Department of Paediatrics, University Hospital, Lund, Sweden). Respiratory insufficiency syndrome (RIS) in preterm infants with gestational age of 32 weeks and less. Neonatal management and follow-up study. Acta Paediatr Scand, 64: 813, 1975.-The clinical entity of respiratory insufficiency syndrome (RIS), i.e. irregular breathing leading to recurrent apnea and bradycardia in an otherwise healthy preterm infant, has been studied in respect of symptomathology and management with intensive case including ventilatory support. During a 4-year period 26 of 103 infants with gestational age S32 weeks and mean birth weight 1304 g (range 710 to 1830 g) developed RIS.In most infants the initial apnea occurred after 2 and before 72 hours post delivery but in some infants later. Because of progressive hypoxemia and acidosis 15 of the 26 RIS infants required JPPV treatment. The 76% survival rate of RIS infants seems to justify intensive care with ventilatory support even in the smallest preterm infants with RIS, especially as the follow-up study performed at 15 months to 3 1 years of age showed neurological sequelae in only 3 of 20 surviving babies, i.e. 15 % sequelae rate.

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Section: Outcomesupporting

confidence: 90%

Respiratory Insufficiency Syndrome (Ris) in Preterm Infants With Gestational Age of 32 Weeks and Less

Carlsson¹,

Svenningsen²

1976

Obstetrical & Gynecological Survey

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“…As shown by Gosselin (1 l), there is a high incidence of intrauterine infection in cases of early rupture of the fetal membranes. Our findings support this view, since in all but one of the 9 cases, where there was a history of early rupture of the membranes, extensive inflammatory changes were found at autopsy (26).…”

Section: Etiologic Factorssupporting

confidence: 86%

“…In contrast to IRDS of the more mature infants, there was seldom time enough for the typical respiratory symptom-Acta Prediat Scand 59 complex to develop; respirator treatment was started at the mean age of 7 hours. On the other hand, there were also cases showing the characteristic respiratory symptoms of IRDS, but where no pulmonary hyaline membranes could be found at autopsy (26). Of the 6 mild cases, 4 showed only transient signs of IRDS like the cases reported by Downes et al (7).…”

Section: Respiratory Symptomsmentioning

confidence: 80%

“…Table 3 presents the clinical data for the expired cases treated on IPPR and grouped according to the survivors into 3 categories of Apnea "Symptomless" Hypoglycemia "Symptomless" "Symptomless" "Symptomless" "Symptomless" RD. The postmortem findings are discussed in detail in the second part of the study (26). From Tables 2 and 3 it is clear that severe RD is almost invariably fatal (only one survivor).…”

Section: Clinical Findingsmentioning

confidence: 97%

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INTENSIVE CARE OF SMALL PREMATURE INFANTS: I. Clinical findings and results of treatment

Vapaavuori

Räihä

1970

Acta Paediatrica

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Summary Clinical findings and results of treatment in a series of 49 premature infants with birth weights between 850 and 1250 g are presented. The “intensive care” included nursing in incubators with high environmental humidity maintaining skin temperature at 36.5°C, umbilical catheterisation (both arterial and venous), intravenous glucose infusions, correction of metabolic acidosis by rapid sodium bicarbonate infusions, oxygen therapy and finally endotracheal intubation and mechanical ventilation. The series was divided into 3 categories according to the severity of respiratory symptoms. There was only one survivor out of 12 cases in the category of severe RD, whereas 14 of 21 with moderate RD and 9 of 16 with slight or no RD survived. The overall survival rate was 45%. The correlation between clinical findings, arterial blood gases and pH, chest X‐rays, response to treatment and outcome in each of the 3 categories is discussed. The preliminary data from our follow‐up studies indicate that there are only a few cases showing signs of permanent brain injury at the age of two years.

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