Intensive Care Unit Length of Stay and Mortality Comparison between On-pump and Off-pump Coronary Artery Bypass Graft

Abstract

Background Coronary artery bypass graft (CABG) techniques, both on-pump (ONCABG) and off-pump (OPCABG), were compared recently in order to seek the most effective technique to reduce the cost of prolonged intensive care unit length of stay (ICU LOS) and mortality. This study aim to compare ICU LOS and mortality in ONCABG and OPCABG Methods Secondary data was used in this study. Statistical analyses were performed in SAS 9.4 (SAS Institute Inc, Cary, NC). The analyses included descriptive statistics for all variables, generalized linear models for ICU LOS, and logistic regression for mortality. All models were fitted in bivariate and multivariate forms to consider multiple factors (i.e., age, sex, race, EF, comorbidities such as hypertension, diabetes, and obesity). Statistical significance was determined at the level of alpha = 0.05. Results Demographic data of 1569 patients shows variance of characteristics. The analysis shows significant and longer ICU LOS in OPCABG (Mean = 0.558; SE = 0.026 vs Mean = 0.408; SE = 0.633; p < 0.001). Similar results were demonstrated after adjustment of covariates effects (OPCABG Mean = 0.816; SE = 0.073 vs ONCABG Mean = 0.661; SE = 0.091). Logistic regression shows that there was no significant difference of mortality in OPCABG and ONCABG, both in the unadjusted (OR = 1.165, 95%, CI = 0.485-2.8) and the adjusted model (OR = 1.165, 95% CI = 0.482–2.817). Conclusion ICU LOS was significantly longer in OPCABG patients than in ONCABG patients. There was no significant difference in mortality between the two groups.