2020
DOI: 10.21203/rs.2.24401/v1
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Intensive immunochemotherapy improves prognosis of young patients with double-expressor lymphoma comparison to non-double-expressor lymphoma: a single-center retrospective cohort study

Abstract: Background Double-expressor lymphoma (DEL), defined as cases with concurrent MYC and BCL2 proteins overexpression, is associated with poor prognosis when treated with R-CHOP alone. Prognostic data on DEL treated with intensive treatment are limited and controversial.Methods We retrospectively report our experiences about 221 consecutive de-novo diffuse large B cell lymphoma patients and analyze the role of intensive therapies for 65 patients with DEL.Results No significant difference in clinical characteristic… Show more

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