Elizabeth Anscombe characterised practical knowledge as knowledge ‘in intention’. As Anscombe recognised, accepting this view involves rejecting certain basic orthodox epistemological assumptions. But even once this is done, a challenge remains for a conception of practical knowledge as knowledge ‘in intention’. For while practical knowledge would appear to be a kind of propositional knowledge, intentions would appear to be a kind of non-propositional attitude. I call this the ‘Structural Challenge’ for an intention-based account of practical knowledge. After rejecting two suggested responses – one which views intentions as propositional attitudes; one which views practical knowledge as non-propositional knowledge – I offer my own solution by showing how simply having and carrying out an intention to φ will ordinarily meet a plausible neutral condition on propositional knowledge. Knowing a fact will in general involve being mentally related to it via a successful exercise of relevant concepts. The account I develop turns on viewing a person’s carrying out an intention to φ as their constituting the fact that they are φ-ing, through a practical exercise of their concept of φ-ing. The resulting account sheds light both on the analogies, and on the crucial formal differences, between practical and theoretical knowledge.