The standard weather station network, belonging to the national weather forecast service, cannot satisfy the requirements of advanced simulation tools because of the network density, time interval of recording, collections of measured values or availability of measured data and its price. Due to the outdoor climate change, urban heat islands and advance in research it is vital to obtain precise data sets for the measured location. Since 2014, also the experimental weather station, which continuously records the wind flow, air temperature, humidity, solar radiation, rain and atmospheric air pressure, is a part of University of Zilina campus.In this paper, measured values of selected climate parameters are analyzed in terms of raw data and also in the case study of two wall types – traditional masonry brick wall and lightweight wooden-frame wall. Behavior of these walls is simulated by the impact of a non-steady state with use of WUFI Pro software. The impact on the hygro-thermal regime of walls – water content, simulated under various boundary conditions, is analyzed and the differences between measured years are quantified.