The particular vision of human, bodily life that has been adopted and developed in the neoliberal era since the 1970s is turning humans into a new kind of creature. Both our behavioral and conceptual notions of what it means to be human have been re-oriented to a vision of the “enterprising self,” the social and political actor who negotiates the world through competition, self-regulation, and rational choice. The concern of this paper is to demonstrate how this framework is theologically unsound and has a destabilizing effect on what constitutes human nature as a particular embodied existence. Attending to the rationale and theological response to the neoliberal logics, this paper seeks to promote a vision of human life and activity that is ordered and oriented to human flourishing and provide examples of resistance to the person-forming capacity of neoliberal social formations.