(J Korean Assoc Oral Maxillofac Surg 2012;38:134-8) Autogenous tooth bone graft material contains organic and inorganic components for osteoinductive and osteoconductive healing. The clinical availability and safety of this material have been confirmed by various experimental and clinical studies. In the future, allogenic and xenogenic tooth bone graft materials, ideal scaffold using teeth for stem cells and bone growth factors, and endodontic and tooth restorative material will be developed.Key words: Tooth, Bone graft material [paper submitted 2012. 4. 6 / accepted 2012. 4. 6] and its osteoconduction capacity is low. Moreover, it cannot be degraded by macrophage. Low-crystalline carbonic apatite has the most effective osteoconduction capacity 1,2 . The chemical compositions of teeth and bone are very similar. Enamel is 96% inorganic ingredients and 4% organic ingredients and water. Dentin has a 65% : 35% ratio, whereas cementum has the ratio of 45-50% : 50-55%. Finally, alveolar bone is made up of 65% inorganic ingredients and 35% organic ingredients. Tooth dentin and cementum contain a number of bone growth factors including type I collagen and bone morphogenic protein (BMP). Type I collagen accounts for 90%, with the rest consisting of noncollagenous proteins, biopolymer, lipid, citrate, lactate, etc. Noncollagenous proteins are phosphophoryn, sialoprotein, glycoprotein, proteoglycan, BMP, etc. They can perform the role of promoting bone resorption and bone formation. Therefore, bone graft materials using teeth are considered to be potentially useful in clinics [3][4][5] .
II. Osteoinduction of TeethDentin matrix has long been proven to be osteoinductive and rich in BMP 6-8 . Organic component accounts for about 20% of dentin weight and mostly consists of type I collagen. Moreover, it was proven to have BMP promoting cartilage and bone formation, differentiating undifferentiated mesenchymal stem cells into chondrocytes and osteogenic cells [9][10][11][12] . Noncollagenous proteins of dentin such as