Intentions to use hormone replacement therapy in a community sample of 45-year-old women

Hunter, Myra; Liao, Ke-Ru

doi:10.1016/0378-5122(94)90096-5

Cited by 39 publications

(16 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For example, a woman's experience of negative side effects, menopausal symptoms, interpersonal relationships, and external in uences, such as ageism and sexism, are key determinants of decision making regarding intentions to use HRT (Marmoreo et al, 1998). A disinclination to use drugs and interfere with a natural process were key reasons for 42% of a sample of 90 women not intending to use HRT (Hunter & Liao, 1994).…”

Section: Introductionmentioning

confidence: 97%

See 1 more Smart Citation

The willingness of women to participate in a long-term trial of hormone replacement therapy: A qualitative study using focus groups

Hepworth¹,

Paine²,

Miles³

et al. 2002

Psychology, Health & Medicine

View full text Add to dashboard Cite

The actual proportion of eligible people who participate in clinical trials is low. Consequently, a qualitative study of the willingness of women who are postmenopausal to participate in a long-term randomized control trial of hormone replacement therapy (HRT) designed to investigate the prevention of degenerative diseases was conducted. Focus group methodology was employed to explore the personal and social aspects of decision making about trial participation. Participants were randomly selected from the patient age-sex registers of four University of Adelaide general practices. Twenty-one women participated in four focus groups. The reasons for and against trial participation were examined using qualitative content analysis; (n 5 18) women were unwilling to participate in the trial. The lack of perceived individual bene t, minimal altruism, the risk of breast cancer and side effects, not wanting to take unnecessary medication, a ten-year commitment, and negative experiences of HRT use, were the main reasons given for not entering the trial. Of the few women (n 5 3) who clearly would enter the trial, free prescriptions and a positive history of using HRT were the main reasons for participation. The perceived disadvantages of clinical trials of HRT deter women from participating in a long-term clinical trial of HRT. An investment in education and information to eligible participants about both the risks and potential bene ts of HRT may improve trial recruitment.

show abstract

Section: Introductionmentioning

confidence: 97%

“…Although previous studies have shown approximately 71% support for participation in trials 470 J. HEPWORTH ET AL. by patients and the public regarding oncology and cardiology treatments (Cassileth et al, 1982), the actual proportion of eligible patients who participate is low (Hunter & Liao, 1994;Schain, 1994).…”

Section: Introductionmentioning

confidence: 99%

The willingness of women to participate in a long-term trial of hormone replacement therapy: A qualitative study using focus groups

Hepworth¹,

Paine²,

Miles³

et al. 2002

Psychology, Health & Medicine

View full text Add to dashboard Cite

show abstract

“…Nearly 65% of the women in a study performed in Chile in 2001 stated that they had insufficient knowledge of HT and menopause 24 . A British study by Hunter and Liao 36 showed that 45 year-old women had little knowledge of menopause and its causes.…”

Section: Knowledge In Relation To Ht Usementioning

confidence: 99%

Knowledge of reproductive physiology and hormone therapy in 53- to 54-year-old Swedish women

Lindh-Åstrand

Brynhildsen²,

Hoffmann³

et al. 2007

Menopause

View full text Add to dashboard Cite

Knowledge of reproductive physiology and hormone therapy in 53-to 54-year-old Swedish women: a population-based study., 2007, Menopause, (14) Women with low educational level were more likely to answer the questions by stating that they were unsure than did women with high educational level. Ever users of HT knew more than never-users about risks and benefits of HT in relation to breast cancer and osteoporosis, and ever-users thought that the risks of thrombosis and myocardial infarction were lower than did never-users. Conclusions:Women need improved knowledge of the risks and benefits of HT as well as education about the reproductive system around menopause. This would probably better support and empower menopausal women to manage an important period of their lives.

show abstract

“…However, several studies report that women on HRT are different in many aspects from those of nonusers. Women who intend to use HRT have a more negative attitude toward menopause, lower levels of self-esteem, and higher levels of depressed mood and anxiety (Hunter and Liao 1994). Women willing to use HRT during menopause may receive higher benefits in mood.…”

Section: Discussionmentioning

confidence: 99%

Mood Scores in Relation to Hormone Replacement Therapies during Menopause: A Prospective Randomized Trial

Önalan

Selam

et al. 2005

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

There is lack of studies in literature about the long-term effects of hormone replacement therapies and cholesterol levels on mood scores in menopause. In the present study we have investigated whether serum lipid levels affect mood scores in menopause and evaluated the long-term effects of the combined hormone replacement regimens (HRT) on depressive symptoms in postmenopausal women. In this prospective-randomized, placebo-controlled, double-blind study, 286 women in menopause were divided into four groups according to therapeutic regimens they received; 1) Conjugated equine estrogen (CEE) of 0.625 mg plus medroxyprogesterone acetate (MPA) of 2.5 mg (n = 79), 2) CEE (0.625 mg) plus MPA of 5 mg (n = 77), 3) tibolone of 2.5 mg (a selective tissue estrogenic activity regulator) (n = 76), and 4) Calcium (Ca) of 1,000 mg (n = 54). Beck Depression Inventory (BDI), and serum levels of lipoprotein lipids were assessed before and after 12-months of treatment with oral continuous HRT and Ca supplementation. BDI scores in the study groups were not correlated with lipid profiles. We compared two subgroups of patients with initial BDI scores 0-14 (normal mood scores) in order to asses for the possible relation between the lipid profile and mood. Following treatment, first subgroup had increased scores to 15-30 (mildly depressed women, n = 27) and the second subgroup preserved BDI scores of 0-14 (normal mood scores, n = 23). Serum levels of total cholesterol, high-density lipoprotein, lowdensity lipoprotein and body mass index were found to be similar between these two groups. BDI scores decreased significantly in all HRT groups after 12 months of treatment, compared to Ca group ( p < 0.05). We did not observe any correlation between BDI scores and lipid profiles before and following continuous HRT or Ca supplementation. Continuous combined hormone replacement regimens, CEE + MPA and tibolone, have superior long-term effects on mood scores in menopause and should be considered during

show abstract

Intentions to use hormone replacement therapy in a community sample of 45-year-old women

Cited by 39 publications

References 22 publications

The willingness of women to participate in a long-term trial of hormone replacement therapy: A qualitative study using focus groups

The willingness of women to participate in a long-term trial of hormone replacement therapy: A qualitative study using focus groups

Knowledge of reproductive physiology and hormone therapy in 53- to 54-year-old Swedish women

Mood Scores in Relation to Hormone Replacement Therapies during Menopause: A Prospective Randomized Trial

Contact Info

Product

Resources

About