This article presents a comparison between different attachment systems used to retain and support maxillary and mandibular overdentures in completely edentulous patients. A literature review based on a MEDLINE search limited to English-language articles published from 1988 to the present was performed, and a large number of attachments available in the dental market were reviewed with regard to several factors, including: (1) implant survival rate, (2) marginal bone loss, (3) soft tissue complications, (4) retention, (5) stress distribution, (6) space requirements, (7) maintenance complications, and (8) patient satisfaction. These factors are considered essential for the successful outcome and good long-term prognosis of the prostheses. Selection criteria previously published in the literature are discussed as well. Product names and manufacturers are mentioned only if related to attachment systems, as they are cited in the original articles.