Inter- and Intra-rater Reliability of Pattern Identification Using Nasal Endoscopy for Allergic Rhinitis

Kim, Kyuseok; Yun, Younghee; Park, Jeong-Su; Kim, Nam-Kwen; Kim, Kyung-Jun; Kim, Hee-Taek; Hong, Seung-Ug; Jang, Bo-Hyeong; Yoon, Hwa-Jung; Choi, In-Hwa; Ko, Seong‐Gyu

doi:10.6114/jkood.2013.26.2.010

Cited by 6 publications

(3 citation statements)

References 4 publications

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“…If a score is obtained between 11 and 21 in the 1st questionnaire, the 2nd questionnaire is not completed, but if 10 or fewer points are obtained, the 2nd questionnaire is conducted. [25] The 1st questionnaire consists of seven symptoms (facial color, digestive problems, gas, stool condition, general condition, appetite, and body mass index using a four-point Likert scale from 0 to 3 [0 = no symptoms, 1 = Occasionally, 2 = Frequently, 3 = Always]). The 2nd questionnaire also consists of seven questions (coldness, drinking water, general facial color, detailed stool condition, urine color, rhinorrhea's viscosity and color, and nasal endoscopy status.…”

Section: Discussionmentioning

confidence: 99%

“…KiFDA 3.0 consists of two questionnaires. If a score is obtained between 11 and 21 in the 1st questionnaire, the 2nd questionnaire is not completed, but if 10 or fewer points are obtained, the 2nd questionnaire is conducted [25] . The 1st questionnaire consists of seven symptoms (facial color, digestive problems, gas, stool condition, general condition, appetite, and body mass index using a four-point Likert scale from 0 to 3 [0 = no symptoms, 1 = Occasionally, 2 = Frequently, 3 = Always]).…”

Section: Methodsmentioning

confidence: 99%

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Combined Korean medicine therapies in children with allergic rhinitis

Chu¹,

Jang

Lee

et al. 2021

Medicine

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Introduction: Allergic rhinitis (AR) is the third most prevalent disease in early and middle adolescence in South Korea and one of the most common allergic diseases worldwide. Due to the ineffectiveness and frequent side effects of conventional medications for AR (such as antihistamines, corticosteroids) complementary and alternative medical (CAM) therapies have been in the spotlight. Although previous clinical trials conducted on AR with CAM showed efficacy and safety, these research results have limitations in that they did not estimate the effectiveness of combining multiple interventions. In this respect, this study aims to investigate the efficacy and safety of combined Korean medicine therapy by establishing an observational registry study at 13 Korean medical clinics that specialize in treating pediatric rhinitis. Methods: This is a prospective, observational, registry study of adolescent patients with AR. After screening, eligible subjects will be allocated to the registry. The patients will undergo a 4-week treatment and a 4-week post-treatment follow-up. The primary outcome will be the change in the average total nasal symptom score evaluated from baseline to the end of treatment. The secondary outcomes will include the numerical range scale, quality of life questionnaire in Korean children with AR, and the Pediatric Allergic Disease Quality of Life Questionnaire. KiFDA 3.0 will be measured for explanatory application on adolescents. Medical cost data and characteristics of patients such as weight, height, and sex will be collected by researchers. Discussion: This is the first multi-center observational registry study to compare combined Korean medicine treatment for AR. The results of this study will shed light on the effectiveness and safety of Korean medicine treatments for the treatment of patients with AR. Trial registration: KCT0006625 (2021.09.30)/IRB approval: Kyung-hee University Institutional Review Board (approval number: KHSIRB-21-358-1 [NA]). Trial Status: Protocol version 1.2(2021.09.16).

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Combined Korean medicine therapies in children with allergic rhinitis

Chu¹,

Jang

Lee

et al. 2021

Medicine

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“…An overall assessment of AR was performed after treatment [27]. Pattern identification (PI) questionnaire for AR [28] and the Sasang constitution questionnaire [29] were used to provide a comprehensive interpretation based on traditional Korean medicine.…”

Section: Secondary Outcomesmentioning

confidence: 99%

Efficacy and Safety of Bojungikgi-Tang for Persistent Allergic Rhinitis: A Randomized, Double-Blinded, Placebo-Controlled, Phase II Trial

Lee,

Woo,

Lyu

et al. 2024

Healthcare

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Conventional treatments for allergic rhinitis (AR) exhibit insufficiency and long-term use-related side effects. Considering the reported anti-inflammatory and immunoregulatory effects of Bojungikgi-tang (BJIGT), we aimed to assess its efficacy on persistent AR (PAR). Patients with PAR were randomly assigned in a 1:1:1 ratio into high-dose BJIGT, standard-dose BJIGT, and placebo groups, followed by 1-week run-in and 4-week treatment periods. The primary outcome included the mean change in Total Nasal Symptom Score (TNSS), with secondary outcomes encompassing the Korean Allergic Rhinitis-Specific Quality of Life Questionnaire, biomarkers, overall assessment, TNSS by AR pattern identification, and the Sasang constitution. The mean TNSS change was more improved in the BJIGT group than in the placebo group; however, no statistically significant differences were observed. Additional interaction effect analysis revealed a statistically significant improvement in the high-dose BJIGT group compared with the placebo group from weeks 1–2 to weeks 3–4. Regarding secondary outcomes, the BJIGT group exhibited similar or improved results compared with the placebo group, showing no statistically significant differences. No serious adverse effects or clinically significant changes in safety assessments were observed. Given that this study validated clinical improvement and safety, it serves as potential groundwork for pertinent future studies.

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