Inter- and Intraobserver Agreement of ¹⁸F-FDG PET/CT Image Interpretation in Patients Referred for Assessment of Cardiac Sarcoidosis

Qualitative and Quantitative Assessments of Cardiac Sarcoidosis Using ¹⁸F-FDG PET

“…In the most common classification of cardiac 18 F-FDG uptake image patterns was improved by detailed pre-scan dietary preparation (12). 18 F-FDG uptake is expected to be useful not only to diagnose but also to predict the cardiac events related to CS.…”

Recommendations for ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography Imaging for Diagnosis of Cardiac Sarcoidosis—2018 Update

“…Other researchers (47,48) reported that localized 18 F-FDG uptake in this region does not indicate positivity for cardiac sarcoidosis. Other reports pointed out that localized 18 F-FDG uptake in the anteroseptal base and diffuse uptake in the entire circumference of the heart base could be physiological myocardial uptake (29,79). Therefore, this remains a controversial issue.…”

Statistics Refresher for Molecular Imaging Technologists, Part 2: Accuracy of Interpretation, Significance, and Variance

“…An example of the kappa measurement in PET literature is a recent study by Ohira et al (5) which looked at inter-reader and intra-reader reliability of PET FDG in patients being referred for cardiac sarcoidosis. The authors measured reader agreement using two interpretation strategies: reading scans in pattern categories (focal, focal on diffuse, no uptake, diffuse, or isolated lateral and /or basal) and in a binary fashion (positive scan consistent with cardiac sarcoidosis or negative scan.)…”