Inter-Edge and Cloud conversion accelerated user-generated content for virtual brand community

Song, Meng­meng; Duan, Yucong; Huang, Tianyi; Zhan, Lougao

doi:10.1186/s13638-019-1635-6

Cited by 13 publications

(8 citation statements)

References 63 publications

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“…Data, information, knowledge and wisdom (DIKW) model has been widely used in life in all aspects including medicine ( Song et al, 2018 , 2020 ; Duan, 2019a , b ; Duan et al, 2019a , b ). In recent years, genome-wide profiling has substantially advanced our understanding of the genetic landscape and driver pathways leading to HCC ( Totoki et al, 2014 ; Schulze et al, 2015 ; Zucman-Rossi et al, 2015 ; Ally et al, 2017 ; Villanueva, 2019 ), revealing Cellular tumor antigen p53 ( TP53 ), Catenin beta-1 ( CTNNB1 ), Axin-1 ( AXIN1 ), Telomerase reverse transcriptase ( TERT ) promoter and other key genes as driver mutations, and WNT/β-catenin, p53 cell cycle pathway, oxidative stress, PI3K/AKT/MTOR, and RAS/RAF/MAPK pathways as key signaling pathways involved in liver carcinogenesis.…”

Section: Introductionmentioning

confidence: 99%

Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma

Li¹,

Chen

Yang³

et al. 2020

Front. Genet.

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Hepatocellular carcinoma (HCC) accounts for approximately 85–90% of all liver cancer cases and has poor relapse-free survival. There are many gene expression studies that have been performed to elucidate the genetic landscape and driver pathways leading to HCC. However, existing studies have been limited by the sample size and thus the pathogenesis of HCC is still unclear. In this study, we performed an integrated characterization using four independent datasets including 320 HCC samples and 270 normal liver tissues to identify the candidate genes and pathways in the progression of HCC. A total of 89 consistent differentially expression genes (DEGs) were identified. Gene-set enrichment analysis revealed that these genes were significantly enriched for cellular response to zinc ion in biological process group, collagen trimer in the cellular component group, extracellular matrix (ECM) structural constituent conferring tensile strength in the molecular function group, protein digestion and absorption, mineral absorption and ECM-receptor interaction. Network system biology based on the protein–protein interaction (PPI) network was also performed to identify the most connected and important genes based on our DEGs. The top five hub genes including osteopontin ( SPP1 ), Collagen alpha-2(I) chain ( COL1A2 ), Insulin-like growth factor I ( IGF1 ), lipoprotein A ( LPA ), and Galectin-3 ( LGALS3 ) were identified. Western blot and immunohistochemistry analysis were employed to verify the differential protein expression of hub genes in HCC patients. More importantly, we identified that these five hub genes were significantly associated with poor disease-free survival and overall survival. In summary, we have identified a potential clinical significance of these genes as prognostic biomarkers for HCC patients who would benefit from experimental approaches to obtain optimal outcome.

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Section: Introductionmentioning

confidence: 99%

Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma

Li¹,

Chen

Yang³

et al. 2020

Front. Genet.

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“…) then (7) x best,G+1 ⟵ x i,G+1 (8) end if ALGORITHM 4: Selection(u i,G+1 , x i,G , x best,G+1 ) also have to tune some system parameters for illuminating the effectiveness of our approach.…”

Section: Methodsmentioning

confidence: 99%

“…Edge computing is an emerging technique of optimizing computing systems by performing data processing at the edge of the network near the source of the original data [5]. It pushes applications, data, and services away from centralized points (i.e., the cloud) to the logical extremes of a network, and thus, the communication latency for processing user requests can be significantly reduced [6,7], as well as fault-tolerance [8], privacy [9][10][11][12], and security [13] being enhanced. With edge computing architecture, the performance as well as scalability of GIS systems can be dramatically enhanced [14].…”

Section: Introductionmentioning

confidence: 99%

Deploying GIS Services into the Edge: A Study from Performance Evaluation and Optimization Viewpoint

Zhang

Huang

2020

Security and Communication Networks

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Geographic information system (GIS) is an integrated collection of computer software and data used to view and manage information about geographic places, analyze spatial relationships, and model spatial processes. With the growing popularity and wide application of GIS in reality, performance has become a critical requirement, especially for mobile GIS services. To attack this challenge, this paper tries to optimize the performance of GIS services by deploying them into edge computing architecture which is an emerging computational model that enables efficient offloading of service requests to edge servers for reducing the communication latency between end-users and GIS servers deployed in the cloud. Stochastic models for describing the dynamics of GIS services with edge computing architecture are presented, and their corresponding quantitative analyses of performance attributes are provided. Furthermore, an optimization problem is formulated for service deployment in such architecture, and a heuristic approach to obtain the near-optimal performance is designed. Simulation experiments based on real-life GIS performance data are conducted to validate the effectiveness of the approach presented in this paper.

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“…Internalization generates a tighter psychological bond with the community and inspires people to achieve the community's goals. Achieving primary psychological desires has a significant role in the endorsement of the internalization of personal motivation, which in turn brings better satisfaction and greater involvement of a person and encourages him or her to continue with a particular activity for an extended period and bring more positive behavioral outcomes (Song et al, 2020). A person's internal motivation is high when he/she feels a high level of autonomy in a task: this also enhances the level of interest and engagement (Hsieh and Chang, 2016).…”

Section: Brand Co-creation Antecedentsmentioning

confidence: 99%

Brand co-creation through participation of organization, consumers, and suppliers: an empirical validation

Sarkar

Banerjee

2020

JPBM

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Purpose The purpose of this paper is to empirically validate the role of different stakeholders in a co-creation context. In this paper, a new triadic brand co-creation concept has been presented highlighting why consumers participate in brand co-creation, what is the role of the organizing company and what is the role of suppliers in such event and what are the benefits each of these three stakeholders receives in-turn of participating in such an event. Design/methodology/approach A quantitative approach has been adopted in this study using structural equation modeling to verify brand co-creation from the triadic stakeholder participation standpoint. Findings The empirical study validates that consumer’s perceived psychological benefits, brand self-connection and participation in brand communities all have a positive impact on the brand co-creation process. The results also suggest co-creating organizations should create an environment of trust and openness in such a brand co-creation event and they should show participatory leadership and provide proper tools and training to the participating consumers. The participating suppliers should show higher levels of professionalism, they should be willing to invest in research and development (R&D) and collaborate with organizations in their R&D effort. The results also validate that the brand co-creation event ensures increased brand knowledge and value of consumers. Also, brand co-creation is positively related to purchasing, helping others and consumers’ feedback intention. Through brand co-creation sponsoring organizations creates innovation and reduces resource issues and marketing costs. The results also show that brand co-creation can lead to better brand loyalty among consumers. Suppliers should also be actively engaged in brand co-creation as it leads to a better performance in terms of greater revenue, market offerings and reputation. Research limitations/implications The research investigates all aspects of inputs and benefits of the three different stakeholders – consumers, organizations and suppliers. It gives a comprehensive framework to validate the roles and benefits of each of the stakeholders from a consumer’s viewpoint. It conceptualizes and validates the constructs to provide the holistic concept and its associated framework. Practical implications The findings offer new insights to brand managers, Chief Experience Officers of how a brand co-creation event can be organized successfully, what should be the role of them, how they should involve suppliers in this kind of an event and finally how this kind of event can have a long-term impact on the brand in question. Originality/value This is the first empirical research on brand co-creation which investigates the roles and benefits from a triadic stakeholders’ standpoint. This study also analyzes and validates the comprehensive framework of brand co-creation proposed.

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Inter-Edge and Cloud conversion accelerated user-generated content for virtual brand community

Cited by 13 publications

References 63 publications

Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma

Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma

Deploying GIS Services into the Edge: A Study from Performance Evaluation and Optimization Viewpoint

Brand co-creation through participation of organization, consumers, and suppliers: an empirical validation

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