2018
DOI: 10.1007/s13566-018-0366-3
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Inter-fraction movements of the prostate and pelvic lymph nodes during IGRT

Abstract: ObjectivitiesThe aim of this study was to evaluate inter-fraction movements of lymph node regions that are commonly included in the pelvic clinical target volume (CTV) for high-risk prostate cancer patients. We also aimed to evaluate if the movements affect the planning target volumes.MethodsTen prostate cancer patients were included. The patients underwent six MRI scans, from treatment planning to near end of treatment. The CTV movements were analyzed with deformable registration technique with the CTV divide… Show more

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Cited by 11 publications
(6 citation statements)
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References 30 publications
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“…During review it was noted that the prostate bed can move independently to the lymph node volumes. This has been reported previously in definitive prostate radiotherapy [ 15 ]. Our matching technique priorities matching to the prostate bed and checking that the soft tissue delineated in the lymph node CTV on the planning CT scan is included in the lymph node PTV on the CBCT scan.…”
Section: Discussionsupporting
confidence: 82%
“…During review it was noted that the prostate bed can move independently to the lymph node volumes. This has been reported previously in definitive prostate radiotherapy [ 15 ]. Our matching technique priorities matching to the prostate bed and checking that the soft tissue delineated in the lymph node CTV on the planning CT scan is included in the lymph node PTV on the CBCT scan.…”
Section: Discussionsupporting
confidence: 82%
“…Tumour and reference VOIs were transferred automatically with r + DIR techniques, from baseline diffusion-weighted image b = 200 s/mm 2 to the examination three months later, after ADT. The r + DIR technique compensated for prostate motion [25] and deformation, but also image distortions. After visual inspection of the registrations and VOIs, 16 patients had an individualised optimisation of the Elastix parameters.…”
Section: Methodsmentioning
confidence: 99%
“…During SBRT of lymph node oligometastases on CBCT-linacs, inter-fraction motion is accounted for by couch translations and sometimes also for rotations. These translations and rotations can compensate for rigid target motion, but not for non-rigid changes of the target such as changes in size or shape or, for multiple lymph nodes, independent motion of the targets [14,15]. Additionally, it is not possible to account for anatomical changes in the location of the target and OARs, as well as path length changes and tissue attenuation.…”
Section: Introductionmentioning
confidence: 99%