Inter-individual variations of human mercury exposure biomarkers: a cross-sectional assessment

Berglund, Marika; Lind, Birger; Björnberg, Karolin Ask; Palm, Brita; Einarsson, Östen; Vahter, Marie

doi:10.1186/1476-069x-4-20

Cited by 265 publications

(187 citation statements)

References 37 publications

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“…The main part of Hg is bound to hemoglobin in the red blood cells (RBCs) (Ancora et al, 2002;Berglund et al, 2005). Therefore, changes in hemoglobin concentration (or in hematocrit) can affect Hg levels measured in whole blood.…”

Section: Discussionmentioning

confidence: 99%

Blood dynamics of mercury and selenium in northern elephant seals during the lactation period

Habran

Debier

Crocker

et al. 2011

Environmental Pollution

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a b s t r a c tThe effects of reproduction and maternal investment (i.e., milk transfer) on trace element levels remain poorly understood in marine mammals. We examined the blood dynamics of mercury (Hg) and selenium (Se) during lactation in the northern elephant seal (Mirounga angustirostris), a top predator from the North Pacific Ocean. Total Hg and Se levels were measured in whole blood and milk of 10 motherepup pairs on days 5 and 22 of lactation. Both Hg and Se were transferred to offspring through the milk. Results suggested that the maternal transfer of Se was prominent during lactation, whereas the Hg transfer was larger during gestation. The lactation period affected Hg and Se levels in the blood of elephant seal mothers and pups. Physiological processes and their relationship to body condition should be considered carefully when interpreting trace element levels in the framework of biomonitoring.

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Section: Discussionmentioning

confidence: 99%

Blood dynamics of mercury and selenium in northern elephant seals during the lactation period

Habran

Debier

Crocker

et al. 2011

Environmental Pollution

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“…We used RBC and hair as the exposure indices of MeHg based on evidence that more than 90 % of T-Hg in RBC and hair is MeHg (18) . It has been reported that permanent waving decreases the mercury concentration in hair (19,20) , but Ohba et al (21) reported that the average mercury concentration of 3-cm segments of hair from the proximal end showed no significant decrease by permanent waving.…”

Section: Determination Of Total Mercury In Biological Samplesmentioning

confidence: 99%

Assessment of exposure to methylmercury in pregnant Japanese women by FFQ

Yaginuma-Sakurai

Shimada

Ohba

et al. 2009

Public Health Nutr.

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Objective: To examine whether an FFQ can be used for assessing exposure to methylmercury (MeHg) by estimating MeHg intake from seafood consumption using the FFQ and confirming the accuracy of the estimated value. Design: Seafood consumption of pregnant women was assessed using the FFQ. Total mercury (T-Hg) concentrations of maternal red blood cells (RBC) and hair were measured as exposure indices of MeHg. Setting: A prospective birth cohort study, the Tohoku Study of Child Development (TSCD), which has been ongoing since 2001. Subjects: The subjects were 609 pregnant Japanese women who were enrolled in the TSCD. Results: MeHg intake was estimated from seafood consumption determined using the FFQ and the MeHg concentrations in each type of seafood. The accuracy of the estimated value was confirmed by comparison with T-Hg in RBC and hair. Estimated MeHg intake was 42?3 mg/week, and 43?0 % of that was from large predatory fish. Compared with the Japanese tolerable weekly intake, in total 12?5 % of the subjects exceeded it. T-Hg concentrations in RBC and hair were significantly correlated with estimated MeHg intake: r 5 0?325 (P , 0?0001) for RBC and r 5 0?305 (P , 0?0001) for hair. Conclusions: Estimated MeHg intake based on the FFQ was significantly associated with T-Hg concentrations in RBC and hair. Although the estimated value involves uncertainties, the FFQ appears to be a useful tool for assessment of exposure to MeHg.

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“…Dado que el MeHg se une de forma preferente a los glóbulos rojos (GR) su medición en GR puede ser un biomarcador más preciso, especialmente en poblaciones con amalgamas dentales y con exposición baja 14 . Sin embargo, los niveles de mercurio en GR y su relación con la ingesta ha sido menos estudiado que en ST y no hay niveles internacionalmente aceptados aún.…”

Section: Mercurio En Sangre Total (St)unclassified