Inter‐instrumental variation of skin capacitance measured with the Corneometer<sup>®</sup>

O’goshi, Ken-ichiro; Serup, Jørgen

doi:10.1111/j.1600-0846.2005.00086.x

Cited by 45 publications

(53 citation statements)

References 7 publications

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“…The improvement in skin moisturising was statistically significant at the abdominal skin application site. The results of the present study are consistent with the literature data [37][38][39][40][44][45][46][47][48]. In particular, the results are consistent with those of Li et al [44], who also showed that the measures taken one hour of the application are predictive of the stratum corneum moisturising obtained after a multiple applications for one or 2 weeks.…”

Section: Discussionsupporting

confidence: 83%

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Tolerability and hydrating effects of an anti-aging gynaecological collagen cream in women in menopause

Stefano¹,

Radicioni²,

Vele³

et al. 2014

OJOG

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Background and Aims: A gynaecological cream containing collagen, phytocollagen, hyaluronate and vitamins was investigated in women in menopause. Methods: The cream was daily applied to the vaginal mucosa and the perineal skin as well as to the abdominal skin (healthy skin used as control) for 1 week and then on alternate days for other 2 weeks. Skin hydration and viscoelasticity were measured at baseline and after 8 and 21 days by Corneometer ® CM 825 and Cutometer ® MPA 850, respectively. The product use comfort and the moisturising of the vaginal mucosa were evaluated by the volunteers through a questionnaire and a visual analogue scale, respectively. Results: The local tolerability was excellent for nearly all of the volunteers (90% -95%) and according both to dermatologist's and gynaecologist's evaluation. Related adverse reactions had a frequency of 15% (10% vulvovaginal burning sensation and 5% vulvovaginal discomfort). The topical hydration increased both in the perineal and the abdominal skin. Hydration increase vs. baseline was more marked on day 8 than on day 21 and was significant in the abdominal skin (p-value < 0.0001). The vaginal moisturising improved significantly (p-value < 0.0001) both on day 8 and 21 vs. baseline. Small changes in the viscoelasticity parameters were observed in both the perineal and the abdominal skin. Few significant improvements were R1 and R8 decreases in the perineum and R0 increase in the abdomen. Conclusions: The tested cream represents a safe product with proven moisturising effect towards the vaginal mucosa when daily applied by menopausal women.

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Section: Discussionsupporting

confidence: 83%

“…It is regarded as a reliable measure of skin conditions and also this method gained validity and use diffusion in dermatology and cosmetics [37][38][39]. The reliability and the reproducibility of these measures were previously demonstrated [40][41][42].…”

Section: Methodsmentioning

confidence: 99%

Tolerability and hydrating effects of an anti-aging gynaecological collagen cream in women in menopause

Stefano¹,

Radicioni²,

Vele³

et al. 2014

OJOG

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“…Water is accumulated thanks to the corneal layer of epidermis and the amount of water in this layer is defined as the skin hydration [38]. The correct level of moisture is affected by such factors as the amount of water supplied from the bottom layers of epidermis, dermis and sebaceous glands, and also the amount of water lost through evaporation and the ability of the corneal layer to accumulate water.…”

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confidence: 99%

Structural and biophysical characteristics of human skin in maintaining proper epidermal barrier function

Boer¹,

Duchnik²,

Maleszka³

et al. 2016

pdia

188

178

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A b s t r a c tThe complex structure of human skin and its physicochemical properties turn it into an efficient outermost defence line against exogenous factors, and help maintain homeostasis of the human body. This role is played by the epidermal barrier with its major part -stratum corneum. The condition of the epidermal barrier depends on individual and environmental factors. The most important biophysical parameters characterizing the status of this barrier are the skin pH, epidermal hydration, transepidermal water loss and sebum excretion. The knowledge of biophysical skin processes may be useful for the implementation of prophylactic actions whose aim is to restore the barrier function.Key words: epidermal barrier, sebum, skin hydration, transepidermal water loss, skin pH. Skin is a barrier between the human body and the external environment. It protects the body against exogenous chemical and physical factors, takes part in the metabolic processes, plays a resorptive and thermoregulatory function, being the first line of defence against pathogenic microorganisms, and it partakes in immunological processes [1]. Review paperThe complex structure of human skin and its physicochemical characteristics turn it into an effective outermost defence line against exogenous factors, and help maintain homeostasis of the human body. This role is played by the epidermal barrier, in which the corneal layer of epidermis has a particularly important function to perform [1][2][3]. It consists of 15-20 layers of fully cornified keratinocytescorneocytes. In the bottom part of the cornified layer, the cells closely adjoin each other, while in the top part they are arranged loosely and undergo scaling. Construction of the corneal layer resembles a wall in which corneocytes stand for bricks, and a fat-abundant intercellular matrix is the cement [4,5]. The interior of the corneal layer cells is filled with cytokeratin filaments bonded with filaggrin. These cells are surrounded by a stiff, cornified encasement built mostly of the loricrin protein, forming a part of the so-called protein-lipid envelope [2,3,6]. The envelope is connected with the extracellular liquid crystal matrix and constitutes the border between the hydrophilic surface of the cells and the lipophilic non-polar fatty acids of the matrix surrounding corneocytes [7].The thickness of the outer layer of the epidermis, the size of corneocytes, and the composition of superficial lipids impact the regenerative properties of the skin, which contributes to the various courses of dermatological diseases, and the process of healing alike. Anatomical areas with thick epidermis are more resistant to external factors [8]. On the other hand, the areas with a relatively thin cornified layer, such as the face, are characterized by high susceptibility to damaging factors, but also by the ability to re-establish the barrier function very fast. It is connected with a high proliferative activity, thus quick regeneration of the epidermis, intensive vascularity, good hydration, and pr...

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“…The measurement of skin surface hydration has gained considerable interest in recent years because the water content of the SC influences various physical characteristics of the skin such as barrier function, drug penetration, and mechanical properties. The different noninvasive hydration measurement systems, and the information they provide, are not same; while the measurement result with the MoistureMeter® (Delfin Technologies, Kuopio, Finlandia) is dependent both on the hydration of the SC and the thickness of the dry layer of the SC, the Corneometer 825® (Courage & Khazaka Electronic GmbH, Cologne, Germany) provides a hydration value for a constant depth, (in the first 10-20 μm of the stratum corneum) (5,7,8,10). We should emphasize the high motivation of the participants since there was no abandonment, in spite of the 3 months duration of the study.…”

Section: Discussionmentioning

confidence: 99%

“…The Corneometer 825® (Courage & Khazaka Electronic GmbH, Cologne, Germany) is a capacitive device for measuring the hydration of the SC and gives important information on the biophysical properties and function of the skin barrier. With an adequate amount of water in the SC, the skin maintains an intact barrier function (6)(7)(8)(9)(10). The lips and the perioral region are poorly protected from the sun and this area is continually exposed to solar radiation, the surface of the lower lip receives the highest exposure to ultraviolet light in the whole facial region (4,11,12).…”

Section: Introductionmentioning

confidence: 99%

Study of lip hydration with application of photoprotective lipstick: influence of skin phototype, size of lips, age, sex and smoking habits

López‐Jornet¹,

Camacho-Alonso²,

Rodríguez-Espin³

2010

Med Oral

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Objectives: To study lip hydration levels when applying a lipstick sunscreen for 3 months and to evaluate the influence of size of lips, age, sex, smoking and skin phototype. Study design: The study group was formed by 140 volunteer subjects, one group consisting of 70 patients applying a commercial lipstick sunscreen three times a day and the other group of 70 controls in which no product was applied. The age range was 20-86 years. The influence in lip hydration levels of age, sex, phototype, size of the lips and smoking habits was studied using a Corneometer 825®

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Inter‐instrumental variation of skin capacitance measured with the Corneometer^®

Cited by 45 publications

References 7 publications

Tolerability and hydrating effects of an anti-aging gynaecological collagen cream in women in menopause

Tolerability and hydrating effects of an anti-aging gynaecological collagen cream in women in menopause

Structural and biophysical characteristics of human skin in maintaining proper epidermal barrier function

Study of lip hydration with application of photoprotective lipstick: influence of skin phototype, size of lips, age, sex and smoking habits

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Inter‐instrumental variation of skin capacitance measured with the Corneometer®

Cited by 45 publications

References 7 publications

Tolerability and hydrating effects of an anti-aging gynaecological collagen cream in women in menopause

Tolerability and hydrating effects of an anti-aging gynaecological collagen cream in women in menopause

Structural and biophysical characteristics of human skin in maintaining proper epidermal barrier function

Study of lip hydration with application of photoprotective lipstick: influence of skin phototype, size of lips, age, sex and smoking habits

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Inter‐instrumental variation of skin capacitance measured with the Corneometer^®