Inter-Rater Reliability of Kampo Diagnosis for Chronic Diseases

Maeda-Minami, Ayako; Yoshino, Tetsuhiro; Horiba, Yuko; Nakamura, Tomonori; Watanabe, Kenji

doi:10.1089/acm.2020.0298

Cited by 5 publications

(4 citation statements)

References 8 publications

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“…All the participating physicians are board-certified specialists in Kampo medicine who also have active conventional medicine licenses. Inter-rater reliability of some of these physicians has been shown previously (Maeda-Minami et al, 2021).…”

Section: Participantsmentioning

confidence: 83%

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Relationship Between Conventional Medicine Chapters in ICD-10 and Kampo Pattern Diagnosis: A Cross-Sectional Study

Wu¹,

Le²,

Maeda-Minami³

et al. 2021

Front. Pharmacol.

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Objectives: The newest revision to the International Classification of Diseases, the 11th edition (ICD-11) includes disease classifications from East Asian medicine, including traditional Japanese medicine (Kampo medicine). These disease classifications allow for comparisons between disease classifications from conventional medicine and Kampo medicine.Design/Location/Subjects/Interventions: This is an exploratory, cross-sectional study exploring the relationship between conventional medicine diagnoses and Kampo medicine diagnoses at a large Kampo clinic in Japan. Patients were seen from October 1st, 2014 to June 30th, 2019 and were 20 years of age or older.Outcome measures: Patients presented with one or more conventional medicine ICD-10 codes into the clinic and were given one descriptor from the ICD-11 within the heat-cold module, excess-deficiency module, and an optional body constituents module. The distribution of these Kampo medicine codes was examined in relation to conventional medicine chapters.Results: 1,209 patients were included in our final analysis. Patient number, ages, sex ratio, and BMI varied within conventional medicine ICD-10 chapters and Kampo medicine descriptor codes. Certain conventional medicine chapters are related to specific Kampo medicine descriptor codes, such as chapter IV (endocrine, nutritional, and metabolic diseases) with excess, heat, and kidney qi deficiency.Conclusion: The advent of the ICD-11 allows for systematic, standardized comparisons between Kampo medicine, and contemporary medicine. In this exploratory study, our findings support the independence of Kampo medicine pattern descriptors with ICD-10 conventional medicine chapters. Code overrepresentations in relation to conventional medicine diseases and by age and sex should be an area of future investigation to best understand how to synergize and improve patient care.

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Section: Participantsmentioning

confidence: 83%

“…This pattern diagnosis was given without regard to the CM diagnosis and was made independently using the TM evaluation. We did consider pattern diagnosis interrater reliability when considering our study's wider internal validity, however a study done previously by our group indicated this was not a major concern (Maeda-Minami et al, 2021).…”

Section: Methodsmentioning

confidence: 99%

Relationship Between Conventional Medicine Chapters in ICD-10 and Kampo Pattern Diagnosis: A Cross-Sectional Study

Wu¹,

Le²,

Maeda-Minami³

et al. 2021

Front. Pharmacol.

Self Cite

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“…This term originated from the ancient Chinese medical textbook "Huangdi Neijing" about 2000 years ago. The continuous implementation of ME-BYO measurement from a young age makes it possible to extend the healthier life expectancy and reduce medical expenses [149][150][151]. To avoid being ME-BYO, sleeping well, performing moderate exercise, and eating a healthy diet are important.…”

Section: Foods With Anti-ageing Effectsmentioning

confidence: 99%

The Potential Use of Vitamin D3 and Phytochemicals for Their Anti-Ageing Effects

Santa,

Kumazawa,

Watanabe

et al. 2024

IJMS

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Unlike other vitamins, vitamin D3 is synthesised in skin cells in the body. Vitamin D3 has been known as a bone-related hormone. Recently, however, it has been considered as an immune vitamin. Vitamin D3 deficiency influences the onset of a variety of diseases. Vitamin D3 regulates the production of proinflammatory cytokines such as tumour necrosis factor-α (TNF-α) through binding to vitamin D receptors (VDRs) in immune cells. Since blood levels of vitamin D3 (25-OH-D3) were low in coronavirus disease 2019 (COVID-19) patients, there has been growing interest in the importance of vitamin D3 to maintaining a healthy condition. On the other hand, phytochemicals are compounds derived from plants with over 7000 varieties and have various biological activities. They mainly have health-promoting effects and are classified as terpenoids, carotenoids, flavonoids, etc. Flavonoids are known as the anti-inflammatory compounds that control TNF-α production. Chronic inflammation is induced by the continuous production of TNF-α and is the fundamental cause of diseases like obesity, dyslipidaemia, diabetes, heart and brain diseases, autoimmune diseases, Alzheimer’s disease, and cancer. In addition, the ageing process is induced by chronic inflammation. This review explains the cooperative effects of vitamin D3 and phytochemicals in the suppression of inflammatory responses, how it balances the natural immune response, and its link to anti-ageing effects. In addition, vitamin D3 and phytochemicals synergistically contribute to anti-ageing by working with ageing-related genes. Furthermore, prevention of ageing processes induced by the chronic inflammation requires the maintenance of healthy gut microbiota, which is related to daily dietary habits. In this regard, supplementation of vitamin D3 and phytochemicals plays an important role. Recently, the association of the prevention of the non-disease condition called “ME-BYO” with the maintenance of a healthy condition has been an attractive regimen, and the anti-ageing effect discussed here is important for a healthy and long life.

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“…In addition, patients with two or more risk factors of metabolic syndrome, including visceral fat obesity, diabetes, hypertension, and dyslipidaemia, tend to experience the onset of deadly heart and cerebrovascular diseases. Therefore, these high-mortality diseases can be prevented by removing these risk factors [91][92][93].…”

Section: The Idea Of Me-byo (Mibyou)mentioning

confidence: 99%

Phytochemicals and Vitamin D for a Healthy Life and Prevention of Diseases

Santa

Watanabe

Kumazawa

et al. 2023

IJMS

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A variety of phytocompounds contained in medical plants have been used as medication, including Kampo (traditional Japanese) medicine. Phytochemicals are one category of the chemical compounds mainly known as antioxidants, and recently, their anti-inflammatory effects in preventing chronic inflammation have received much attention. Here, we present a narrative review of the health-promotion and disease-prevention effects of phytochemicals, including polyphenols, the latter of which are abundant in onions, oranges, tea, soybeans, turmeric, cacao, and grapes, along with the synergetic effects of vitamin D. A phenomenon currently gaining popularity in Japan is finding non-disease conditions, so-called ME-BYO (mibyou) and treating them before they develop into illnesses. In addition to lifestyle-related diseases such as metabolic syndrome and obesity, dementia and frailty, commonly found in the elderly, are included as underlying conditions. These conditions are typically induced by chronic inflammation and might result in multiple organ failure or cancer if left untreated. Maintaining gut microbiota is important for suppressing (recently increasing) intestinal disorders and for upregulating immunity. During the COVID-19 pandemic, the interest in phytochemicals and vitamin D for disease prevention increased, as viral and bacterial infection to the lung causes fatal inflammation, and chronic inflammation induces pulmonary fibrosis. Furthermore, sepsis is a disorder inducing severe organ failure by the infection of microbes, with a high mortality ratio in non-coronary ICUs. However, antimicrobial peptides (AMPs) working using natural immunity suppress sepsis at the early stage. The intake of phytochemicals and vitamin D enhances anti-inflammatory effects, upregulates immunity, and reduces the risk of chronic disorders by means of keeping healthy gut microbiota. Evidence acquired during the COVID-19 pandemic revealed that daily improvement and prevention of underlying conditions, in terms of lifestyle-related diseases, is very important because they increase the risk of infectious diseases. This narrative review discusses the importance of the intake of phytochemicals and vitamin D for a healthy lifestyle and the prevention of ME-BYO, non-disease conditions.

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Inter-Rater Reliability of Kampo Diagnosis for Chronic Diseases

Cited by 5 publications

References 8 publications

Relationship Between Conventional Medicine Chapters in ICD-10 and Kampo Pattern Diagnosis: A Cross-Sectional Study

Relationship Between Conventional Medicine Chapters in ICD-10 and Kampo Pattern Diagnosis: A Cross-Sectional Study

The Potential Use of Vitamin D3 and Phytochemicals for Their Anti-Ageing Effects

Phytochemicals and Vitamin D for a Healthy Life and Prevention of Diseases

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