Inter-serotype comparison of polysaccharides produced by extracellular enzymes from Streptococcus mutans

The fructosyltransferase of Streptococcus salivarius

“…However, fructans are also synthesized from sucrose in vitro by the mutans streptococci such as Streptococcus mutans and Streptococcus rattus (Yakushiji, Inoue & Koga, 1984), strains that produce little or no fructanase (Walker et al, 1983). Other mutans species, such as Streptococcus cricetus and Streptococcus sobrinus, which apparently synthesize much less fructan (Yakushiji et al, 1984), are known to be excellent producers of fructanase.…”

“…However, fructans are also synthesized from sucrose in vitro by the mutans streptococci such as Streptococcus mutans and Streptococcus rattus (Yakushiji, Inoue & Koga, 1984), strains that produce little or no fructanase (Walker et al, 1983). Other mutans species, such as Streptococcus cricetus and Streptococcus sobrinus, which apparently synthesize much less fructan (Yakushiji et al, 1984), are known to be excellent producers of fructanase. Most species of mutans streptococci secrete /?-Dfructosyltransferases (FTFs) capable of synthesizing both /^-(2->6) and /?-(2 ^ l)-fructans, but because the relative rate of hydrolysis of these fructans is 100:3 respectively , it is the /?-(2^ l)-fructans that persist (Corrigan & Robyt, 1979).…”

A novel thermostable α-1,3-glucanase from <i>Streptomyces thermodiastaticus</i> HF 3-3

“…a-1,3-Glucanases is an enzyme that catalyzes the hydrolysis of a-1,3-glycosidic bond of a-1,3-glucan, which is the main component of extracellular polysaccharides produced by oral Streptococci in dental plaque (Li and Bowden, 1994;Yakushiji et al, 1984) and the cell wall of some fungi (Hochstenbach et al, 1998;Sietsma and Wessel, 1977;Zonneveld, 1972). Recently, a-1,3-glucan was also recognized as a virulence factor of some pathogenic fungi (Fujikawa et al, 2009(Fujikawa et al, , 2012Rappleye et al, 2007).…”

Biochemical and Molecular Characterization of a Novel Type of Mutanase from Paenibacillus sp. Strain RM1: Identification of Its Mutan-Binding Domain, Essential for Degradation of Streptococcus mutans Biofilms

“…The pathogenicity of S. mutans is closely related to its ability to synthesize insoluble glucans in an extracellular matrix (51). These molecules are characterized as unique polysaccharides composed of ␣-1,6-glucan (dextran) and ␣-1,3-glucan (mutan) chains (50). The dextrans exhibit water solubility, while the mutans are water insoluble.…”