1999
DOI: 10.1002/(sici)1097-4636(19990905)46:3<331::aid-jbm4>3.3.co;2-1
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Interaction of a plasma-sprayed hydroxyapatite coating in contact with human osteoblasts and culture medium

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Cited by 4 publications
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“…The intracellular phosphate concentration in osteoblasts depends to a high extent on passive and sodium‐dependent transport mechanisms and thus mainly on the extracellular phosphate concentration 41. Labat et al42 described calcium release from plasma‐sprayed calcium‐phosphate ceramics during incubation in culture medium, in both the presence and absence of osteoblasts. In human bone‐marrow stromal cells cultured on calcium‐deficient HAP, carbonated apatite, or amorphous calcium phosphate, the rate of proliferation was reduced and that of differentiation increased 7, 8.…”
Section: Discussionmentioning
confidence: 99%
“…The intracellular phosphate concentration in osteoblasts depends to a high extent on passive and sodium‐dependent transport mechanisms and thus mainly on the extracellular phosphate concentration 41. Labat et al42 described calcium release from plasma‐sprayed calcium‐phosphate ceramics during incubation in culture medium, in both the presence and absence of osteoblasts. In human bone‐marrow stromal cells cultured on calcium‐deficient HAP, carbonated apatite, or amorphous calcium phosphate, the rate of proliferation was reduced and that of differentiation increased 7, 8.…”
Section: Discussionmentioning
confidence: 99%
“…To achieve biological fixation of uncemented or press‐fit implants, close apposition of bone to the implant surface and initial mechanical stability are required 5. Osteoconductive coatings not only enhance both the integration of an implant with host bone and the strength of the bone–implant interface, but also prolong the implant's useful life 6. Titanium and titanium alloy implants coated with hydroxyapatite (HA) are widely used to encourage biological fixation,7 due to the biocompatibility and mechanical properties of the metals and the stability and conductivity of the HA 8–10.…”
Section: Introductionmentioning
confidence: 99%
“…Hydroxyapatite (HAp) has high biocompatibility and has been applied to artificial tooth-bone ceramics sinter materials (Akao, 1985) and cell attachment ceramics sinter beds (Suzuki et al, 1990). Many studies on the biocompatibility of HAp have been performed using osteoblasts (Labat et al, 1999;Di Silvio et al, 1998;Wilke et al, 1998). HAp-coated hollow microspheres have been used for 3-dimensional bone tissue formation (Oiu et al, 1999).…”
Section: Introductionmentioning
confidence: 99%