Interaction of ethyl magnesium bromide with 1,1,1,5-tetrachloropentane

Synthesis of Polychloroalkanes

“…Terminal CCl 3 groups in polychloroalkanes can be easily converted to CHCl 2 groups by reaction with EtMgBr [63] or by reduction in the presence of Fe(CO) 5 and a hydrogen donor (dimethylformamide, hexamethylphosphotriamide, isopropanol) [64][65][66][67]. Hydrodechlorination with EtMgBr is accompanied by dimerization (Fig.…”

“…47d) [63] 1) To a solution of 100 g tetrachloropentane in 50 mL ether was added a solution of ethylmagnesium bromide (from 68 g ethyl bromide and 15 g magnesium) m 125 mL ether at such a rate that the ether boiled moderately. Gas consisting of ethane and ethylene was evolved.…”