Interaction of pig manure-derived dissolved organic matter with soil affects sorption of sulfadiazine, caffeine and atenolol pharmaceuticals

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Sulfonamides (SAs) and tetracyclines (TCs) are two classes of widely used antibiotics. There is a lack of easy models for estimating the parameters of antibiotic sorption in soils. In this work, a dataset of affinity coefficients (Kf and Kd) of seven SA/TC antibiotics (i.e., sulfachlorpyridazine, sulfamethazine, sulfadiazine, sulfamethoxazole, oxytetracycline, tetracycline, and chlortetracycline) and associated soil properties was generated. Correlation analysis of these data showed that the affinity coefficients of the SAs were predominantly affected by soil organic matter and cation exchange capacity, while those of the TCs were largely affected by soil organic matter and pH. Pedotransfer functions for estimating Kf and Kd were built by multiple linear regression analysis and were satisfactorily validated. Their performances would be better for soils having higher organic matter content and lower pH. These pedotransfer functions can be used to aid environmental risk assessment, prioritization of antibiotics and identification of vulnerable soils.

Section: Discussionmentioning

confidence: 99%

New Models for Estimating the Sorption of Sulfonamide and Tetracycline Antibiotics in Soils

Tang

et al. 2022

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“…The composite sample (five individual corings) was taken in early spring before the start of the growing season of the winter wheat crop ( Triticum aestivum L.). The soil sample was also used in our previous study [ 46 ] (there, it was sample II of five soil samples). It was selected because it showed good sorption of the tested PhACs and a clear effect of manure DOM on the sorption.…”

Section: Methodsmentioning

confidence: 99%

“…This was done by using urea and potassium dihydrogen phosphate (KH 2 PO 4 ) as major nutrient components, acetic acid and phenol as representatives of volatile organic compounds, and nonadecanoic acid (C:19) as a non-polar organic constituent of manure. The antibiotic sulfadiazine, the beta-blocker atenolol, and the psychotropic drug caffeine were tested as PhACs, which had been previously shown to differently interact with manure fractions [ 46 ]. Thus, this study followed up on previous research to further elucidate sorption in ternary soil–fertilizer–PhAC mixtures [ 46 ].…”

Section: Introductionmentioning

confidence: 99%

“…The antibiotic sulfadiazine, the beta-blocker atenolol, and the psychotropic drug caffeine were tested as PhACs, which had been previously shown to differently interact with manure fractions [ 46 ]. Thus, this study followed up on previous research to further elucidate sorption in ternary soil–fertilizer–PhAC mixtures [ 46 ]. It was hypothesized that the selected model compounds affect the sorption of the PhACs differently.…”

Section: Introductionmentioning

confidence: 99%

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Influence of Manure as a Complex Mixture on Soil Sorption of Pharmaceuticals—Studies with Selected Chemical Components of Manure

Thiele-Bruhn,

Zhang

2023

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Pharmaceutically active compounds (PhACs) enter soil with organic waste materials such as manure. Such complex substrates differently affect PhACs’ soil sorption. For the first time, batch experiments were conducted using five selected chemicals as model constituents to elucidate the effects. Urea, phosphate (KH2PO4), acetic acid, phenol and nonadecanoic acid (C:19) altered the sorption strength and/or nonlinearity of sulfadiazine, caffeine, and atenolol in an arable Cambisol topsoil. The nonlinear Freundlich model best described sorption. Overall, the PhACs’ Freundlich coefficients (sorption strength) increased in the sequence urea < phosphate < phenol < C:19 < acetic acid, while the Freundlich exponents largely decreased, indicating increasing sorption specificity. The effects on sulfadiazine and caffeine were rather similar, but in many cases different from atenolol. Phosphate mobilized sulfadiazine and caffeine and urea mobilized sulfadiazine, which was explained by sorption competition resulting from specific preference of similar sorption sites. Soil sorbed phenol strongly increased the sorption of all three PhACs; phenolic functional groups are preferred sorption sites of PhACs in soil. The large increase in sorption of all PhACs by acetic acid was attributed to a loosening of the soil organic matter and thus the creation of additional sorption sites. The effect of C:19 fatty acid, however, was inconsistent. These results help to better understand the sorption of PhACs in soil–manure mixtures.

“…DOM may have opposite effects on VA sorption to soil [73] (Figure 1). For instance, the addition of manure DOM was reported to decrease sorption K f (the sorption coefficient of the Freundlich model) of chlortetracycline, tylosin, and sulfadiazine to soil, while it increased the sorption K f of sulfamethazine [75,95]. DOM can form complexes with VAs and the complexes may be sorbed onto soil surface, which is a process termed "co-sorption"; DOM may also occupy the active sites on the soil matrix and thus provide additional sorption sites for VA sorption through its multiple moieties, which is a process termed "cumulative sorption" [62,96,97].…”

Section: Water Oxytetracycline Sedimentsmentioning

confidence: 99%

Transport of Veterinary Antibiotics in Farmland Soil: Effects of Dissolved Organic Matter

Gbadegesin

Tang

Liu

et al. 2022

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The application of manure as a fertiliser to farmland is regarded as a major source of veterinary antibiotic (VA) contamination in the environment. The frequent detection of such emerging contaminants and their potential adverse impacts on the ecosystem and human health have provoked increasing concern for VA transport and fate. Extrinsic dissolved organic matter (DOM) may be introduced into farmland soil along with Vas, and thus exert significant effects on the transport of VAs via hydrological processes upon rainfall. The leaching of VAs can be either enhanced or reduced by DOM, depending on the nature, mobility, and interactions of VAs with DOM of different origins. From the aspect of the diversity and reactivity of DOM, the state-of-the-art knowledge of DOM−VA interactions and their resulting effects on the sorption−desorption and leaching of VAs in farmland soil was reviewed. Spectroscopic techniques for examining the extent of binding and reactive components of DOM with VAs are summarized and their usefulness is highlighted. Models for simulating VA transport under the effects of DOM were also reviewed. It is suggested that distinct impacts of DOM of various organic fertiliser/amendment origins should be considered for predicting the transport of VAs in farmland soil.