Interaction of Pt(II) and Pd(II) with oxythiamine: Correlation between ligand basicity and chemical shifts

Zinc(II), cadmium(II) and mercury(II) complexes of the vitamin B1 antagonist oxythiamine

“…The most significant signals in the spectra of the ligand and the complexes (see Section 2) were identified on the basis of previous work on derivatives of oxythiamine [4] and thiamine [3].…”

“…Perhaps one reason for this apparent lack of interest in oxythiamine complexes derives from the early observation that the N(1 0 ) atom of this molecule (usually the donor atom in thiamine complexes) is 500 times less basic than in the vitamin [2]. However, there is spectroscopic [3,4] and X-ray diffraction [5] evidence that oxythiamine, like thiamine, is able to form stable coordination compounds in which it coordinates to the metal atom via N(1 0 ).…”