Fruits and vegetables are important source of essential components in adequate and balanced human diet. The indiscriminate use of synthetic pesticides in production system of fruits and vegetables is of great concern for health and environment safety. Research and Development strategies are presently diverted in search of suitable biological alternatives to replace the pesticide use. Substantial progress has been made in exploring the use of microorganisms in control of plant diseases in integrated plant disease management. One such strategy is the better exploitation of microbes present in soil, which contribute to soil fertility. Certain fungi colonize and form symbiotic association with roots of the plant like mycorrhiza. Significant advances have been made in last two decades to understand the potential of mycorrhizal fungi in suppression of plant pathogens especially soil borne pathogens in wide range of fruits and vegetable host plants. The role of mycorrhiza in management of fruits and vegetable diseases is discussed with their mode of action and future perspectives.