Interaction studies of levofloxacin with human lysozyme in a ternary complex using multispectroscopic and computational analysis: A circular dichroism method for the quantitation of levofloxacin

Khalil, Adila; Kashif, Mohammad

doi:10.1016/j.molliq.2022.121023

Cited by 14 publications

(1 citation statement)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, each of these delivery systems has its own limitations and challenges, such as the complexity of fabrication, potential loss of lysozyme activity during processing, and the need for further clinical validation (Gudipaneni et al, 2014;Omali et al, 2015). Despite these challenges, the advancements in these delivery systems have opened up new avenues for the therapeutic application of lysozyme in wound healing (Gong et al, 2022;Khalil and Mohammad, 2023).…”

Section: Discussionmentioning

confidence: 99%

Exploring the therapeutic potential of recombinant human lysozyme: a review on wound management system with antibacterial

Zhao,

Huang,

2023

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Lysozyme, a natural antibacterial enzyme protein, possesses the ability to dissolve the cell walls of Gram-positive bacteria, demonstrating broad-spectrum antibacterial activity. Despite its significant potential in treating wound infections and promoting wound healing, its widespread clinical application has yet to be realized. Current research is primarily focused on carrier-based delivery systems for lysozyme. In this review, we discuss four delivery systems that can be employed for lysozyme in wound healing treatment, specifically hydrogels, nanofilms, electrospun fibrous membranes, and modified-lysozyme composite systems. These systems not only enhance the stability of lysozyme but also enable its controlled and sustained release at wound sites, potentially overcoming some of the challenges associated with its direct application. Lastly, we delve into the perspectives and challenges related to the use of these delivery systems, hoping to spur further research and innovation in this promising field.

show abstract