Interactions between different selenium compounds and zinc, cadmium and mercury

Feroci, Giorgio; Badiello, R.; Fini, Adamo

doi:10.1016/j.jtemb.2004.09.005

Cited by 84 publications

(52 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The mineral form of Se (selenite) leads to less soluble complexes than organic forms. 35 Interestingly, the current results show that 2θ values are almost the same as those observed after chemical or biological synthesis of CdSe and/or CdS nanoparticles, as reported in many studies. 17,[36][37][38] Differences observed in 2θ values compared to chemical synthesis may be due to temperature variation, ie, the high temperature during chemical synthesis and rat body temperature (about 37°C).…”

supporting

confidence: 89%

Nanotoxicological evaluation of oxidative responses in rat nephrocytes induced by cadmium

Trabelsi¹,

Azzouz²,

Ferchichi³

et al. 2013

IJN

View full text Add to dashboard Cite

supporting

confidence: 89%

Nanotoxicological evaluation of oxidative responses in rat nephrocytes induced by cadmium

Trabelsi¹,

Azzouz²,

Ferchichi³

et al. 2013

IJN

View full text Add to dashboard Cite

“…When Se is administered as a remedy for heavy metal toxicity, it should form insoluble compounds to be excreted in the faeces. Complexes of heavy metals with organic and inorganic sources of Se exhibit different solubility (Feroci et al, 2005). Direct comparison with inorganic Se cannot be made in the present study as it was not used; however, previous work with inorganic Se showed that 0.1 mg/kg Se, as Na 2 SeO 3 , added to diets contained 200 mg/kg of CdCl 2 did not induce any significant changes in the levels of Cd accumulation in rats' kidney, liver (Jihen et al, 2008) and testis (Messaoudi et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

The role of organic selenium in cadmium toxicity: effects on broiler performance and health status

Al-Waeli

Zoidis

Pappas

et al. 2013

Animal

View full text Add to dashboard Cite

This work was part of a project designed to assess whether organic selenium (Se) can protect against the toxic effects of cadmium (Cd). A total of 300 1-day-old, as hatched, broilers were randomly distributed in four dietary treatments with five replicate pens per treatment. In T1 treatment, broilers were fed a diet with 0.3 mg/kg added Se, as Se-yeast, without added Cd; in T2, broilers were fed a diet with 0.3 mg/kg Se and 10 mg/kg Cd; in T3, broilers were fed a diet with 0.3 mg/kg Se and 100 mg/kg of Cd; and in T4 treatment broilers were fed a diet with 3 mg/kg Se and 100 mg/kg Cd. The Cd was added to diets T2, T3 and T4 as CdCl 2 . On the 4th and 6th week, two broilers per replicate pen were killed in order to obtain whole blood, liver, kidney and breast samples. Body mass, feed conversion ratio and mortality were assessed and haematological analyses were performed. Se and Cd levels in tissues were analysed by inductively coupled plasma mass spectrometry. Broilers supplemented with 0.3 mg/kg Se can tolerate low levels of Cd added to the diets, as there were no significant negative effects on the examined performance parameters, whereas addition of excess Cd led to an impairment of broilers' performance. Mortality of broilers did not differ between the four dietary treatments at any interval point or the whole period. The examined haematological parameters such as haematocrit, total blood protein concentration, and leukocytes types ranged within physiological values, revealing no negative health effects after simultaneous Cd and Se addition. The present study indicated that Se can help against the negative effects of Cd, but cannot counteract all of its negative effects.

show abstract

“…For example, it is known that Se food bioavailability in humans is affected by diet composition, presence of other metals, drugs, physiology factors such as nutritional state, growth and pregnancy, and the presence or absence of dietary micronutrient inhibitors or enhancers (Pedrero and Madrid, 2009). Interactions between different Se compounds and zinc, cadmium and mercury have been reported (Feroci et al, 2005). Deficiency or supplementation of an element may alter their balance and trigger antagonistic or synergistic effects.…”

Section: Discussionmentioning

confidence: 99%

Meta-analysis of selenium accumulation and expression of antioxidant enzymes in chicken tissues

Zoidis

Demiris

Kominakis

et al. 2014

Animal

View full text Add to dashboard Cite

A meta-analysis integrating results of 40 selenium (Se) supplementation experiments that originated from 35 different controlled randomized trials was carried out in an attempt to identify significant factors that affect tissue Se accumulation in chicken. Examined factors included: Se source (12 different sources examined), type of chicken (laying hens or broilers), age of birds at the beginning of supplementation, duration of supplementation, year during which the study was conducted, sex of birds, number of chickens per treatment, method of analysis, tissue type, concentration of Se determined and Se added to feed. A correlation analysis was also carried out between tissue Se concentration and glutathione peroxidase activity. Data analysis showed that the factors significantly affecting tissue Se concentration include type of chicken ( P = 0.006), type of tissue ( P < 0.001) and the analytical method used ( P = 0.014). Although Se source was not found to affect tissue Se concentration (overall P > 0.05), certain inorganic (sodium selenite), calcium selenite, sodium selenate and organic sources (B-Traxim Se), Se-yeast, Se-malt, Se-enriched cabbage and Se-enriched garlic as well as background Se level from feed ingredients were found to significantly affect tissue Se concentration. The Se accumulation rate (estimated as linear regression coefficient of Se concentrations to Se added to feed) discriminated between the various tissues with highest values estimated in the leg muscle and lowest in blood plasma. Correlation analysis has also shown that tissue Se concentration (pooled data) was correlated to Se added to feed (r = 0.529, P < 0.01, log values) and to glutathione peroxidase activity (r = 0.332, P = 0.0478), with the latter not being correlated with Se added to feed. Although significant factors affecting Se concentration were reported in the present study, they do not necessarily indicate the in vivo function of the antioxidant system or the level of accumulated Se as other factors, not examined in the present study, may interact at the level of trace element absorption, distribution and retention.

show abstract

Interactions between different selenium compounds and zinc, cadmium and mercury

Cited by 84 publications

References 28 publications

Nanotoxicological evaluation of oxidative responses in rat nephrocytes induced by cadmium

Nanotoxicological evaluation of oxidative responses in rat nephrocytes induced by cadmium

The role of organic selenium in cadmium toxicity: effects on broiler performance and health status

Meta-analysis of selenium accumulation and expression of antioxidant enzymes in chicken tissues

Contact Info

Product

Resources

About