The most common cause of sudden cardiac death (SCD) is coronary artery disease (19, 21) with ventricular tachyarrhythmias as the most frequent underlying mechanism (6). There is a high risk of cardiac arrest recurrence in SCD survivors when the cause of arrhythmia is not reversible (20,32). The majority of resuscitated SCD cases with low risk of recurrence represent the patients that develop malignant arrhythmias in the acute phase of myocardial infarction. Therefore, the precise clinical evaluation for the reversible triggering factors of malignant ventricular arrhythmia, especially acute myocardial infarction (AMI), is important in patients surviving cardiac arrest.In SCD survivors, the use of the standard diagnostic criteria of AMI (1) may be difficult, as the analysis of pre-arrest symptoms is often impossible and both serum cardiac biomarkers and electrocardiogram (ECG) can be influenced by previous cardiac arrest and cardiopulmonary resuscitation.A novel technique that may be used for the diagnosis of AMI is magnetic resonance imaging (MRI). We report its use in four patients after SCD where the diagnosis of AMI could not be definitely established or excluded by means of other diagnostic procedures.
Case reports
Case 1A 54-year-old man collapsed when traveling by public transport. A by-standing medical student diagnosed circulatory arrest and immediately started basic resuscitation. Advanced cardiac life support was given 5 minutes after the onset of the event. Ventricular fibrillation (VF) was terminated by the second defibrillation shock after administration of 1 mg of adrenaline. Restoration of sinus rhythm led to the rapid return of spontaneous circulation (ROSC). On admission at ICU the patient was comatose, haemodynamically stable and artificially ventilated. ECG showed only mild ST segments depressions (<0.1 mV) in the leads V2-4 that were not apparent after 18 hours. Echocardiography described no regional wall motion abnormality with ejection fraction (EF) of 55 %. On admission, there were no laboratory abnormalities explaining the cardiac arrest. Cardiac troponin T (cTnT) became positive (1.0 ng/ml) 18 hours after admission.Mild therapeutic hypothermia was implemented for 24 hours. The patient was extubated 2 days after admission. Confusion and agitation resolved completely in 4 days.Coronary angiogram performed, after 7 days of hospitalization, showed significant (80 % Summary: The ventricular arrhythmias with underlying coronary artery disease are a leading cause of sudden cardiac death (SCD). While the SCD survivors with proven AMI are considered to be at low risk of SCD recurrence, those without the evidence of AMI represent a high risk group that benefits from implantable cardioverter defibrillator. Therefore, the evaluation of SCD survivors for the presence of acute myocardial infarction (AMI) as a triggering factor of cardiac arrest is essential. In SCD survivors, the use of the standard diagnostic criteria of AMI may be difficult, as both serum cardiac biomarkers and electrocardiogram can ...