Interactions between evening and nocturnal cortisol secretion and sleep parameters in patients with severe chronic primary insomnia

Rodenbeck, Andrea; Huether, Gerald; Rüther, Eckart; Hajak, Göran

doi:10.1016/s0304-3940(02)00192-1

Cited by 231 publications

(125 citation statements)

References 15 publications

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“…It is possible that the need for acute antidepressant drug treatment and sleep problems that persist following remission are clinical markers of a biologically distinct depressive subtype that is characterized by hyperarousal and a recurrent or chronic course. Hyperarousal is a state of abnormally high alertness in the sleep environment characterized by the failure to appropriately modulate the metabolic activity of the prefrontal cortex (Nofzinger et al 2004) and the brain's electrical activity during sleep (Krystal et al 2002;Merica et al 1998;Perlis et al 2001), by the sympathetic cardiovascular response (Bonnet and Arand 1997), hypercortisolemia (Rodenbeck et al 2002;Vgontzas et al 2001), and increased systemic metabolism (Bonnet and Arand 1995). Hyperarousal and, more broadly, disruption of the circadian cycle, appears to play a particularly important role in depressed women (Armitage 2007); it may interfere with mood regulation and thus precipitate new depressive episodes in these patients.…”

Section: Effects Of Persistent Insomnia On Moodmentioning

confidence: 99%

Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy?

Dombrovski¹,

Cyranowski²,

Mulsant³

et al. 2008

Depress. Anxiety

104

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Background-Even low levels of residual symptoms are known to increase the risk of relapse and early recurrence of major depression. It is not known if ongoing psychotherapy lessens this risk. We therefore examined the impact of persistent symptoms, including mood, insomnia, and anxiety symptoms, on time to recurrence in women receiving maintenance interpersonal psychotherapy (IPT-M) for recurrent depression.

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Section: Effects Of Persistent Insomnia On Moodmentioning

confidence: 99%

Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy?

Dombrovski¹,

Cyranowski²,

Mulsant³

et al. 2008

Depress. Anxiety

104

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“…There is some evidence to suggest that there is a bidirectional interaction between sleep and stress physiology [44,45]. A review of the interaction between stress and sleep suggests that hyperactivity of the hypothalamo-pituitary adrenal axis can result in sleep fragmentation, decreased slow wave sleep and reduced total sleep time [46].…”

mentioning

confidence: 99%

The effect of working on-call on stress physiology and sleep: A systematic review

Hall

Ferguson

Turner

et al. 2017

Sleep Medicine Reviews

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SUMMARYOn-call work is becoming an increasingly common work pattern, yet the human impacts of this type of work are not well established. Given the likelihood of calls to occur outside regular work hours, it is important to consider the potential impact of working on-call on stress physiology and sleep. The aims of this review were to collate and evaluate evidence on the effects of working on-call from home on stress physiology and sleep. A systematic search of Ebsco Host, Embase, Web of Science, Scopus and ScienceDirect was conducted. Search terms included: on-call, on call, standby, sleep, cortisol, heart rate, adrenaline, noradrenaline, nor-adrenaline, epinephrine, norepinephrine, nor-epinephrine, salivary alpha amylase and alpha amylase. Eight studies met the inclusion criteria, with only one study investigating the effect of working on-call from home on stress physiology. All eight studies investigated the effect of working on-call from home on sleep. Working on-call from home appears to adversely affect sleep quantity, and in most cases, sleep quality. However, studies did not differentiate between night's on-call from home with and without calls. Data examining the effect of working on-call from home on stress physiology were not sufficient to draw meaningful conclusions. KEYWORDSOn-call; standby; sleep quality; sleep quantity; hypothalamo-pituitary adrenal axis; cortisol; sympatho-adrenal medullary system; sleep. ABBREVIATIONSEPHPP: Effective public health practice project PRISMA: Preferred reporting items for systematic reviews and meta-analyses SD: Standard deviation

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“…Hypothalamic-pituitary-adrenal (HPA) axis activity plays a role in hypertension and diabetes development 9,10 . However, data suggesting that HPA hormone levels are higher in insomnia are still inconclusive 11,12,13 .…”

mentioning

confidence: 99%

Objective short sleep duration is associated with the activity of the hypothalamic-pituitary-adrenal axis in insomnia

D’Aurea¹,

Poyares²,

Piovezan³

et al. 2015

Arq. Neuro-Psiquiatr.

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Objective To evaluate the association between objective short sleep duration in patients with insomnia and changes in blood parameters related to hypothalamic-pituitary-adrenal (HPA) axis activity.Method A cross-sectional pilot study was conducted in 30 middle-aged adults with chronic insomnia who were divided into 2 groups according to polysomnography (PSG) total sleep time (TST) (TST > 5h and < 5h). All patients underwent subjective analysis of sleep quality, anthropometric measurements, PSG, and determination off asting blood parameters.Results The results revealed lower sleep efficiency and higher sleep latency for those with a TST < 5h. The subjective sleep quality was worse in the TST < 5h. Significantly, higher glucose and cortisol levels were observed with a TST < 5h. Glucose, cortisol and ACTH levels were inversely correlated with the PSG total sleep time.Conclusion Patients with insomnia with objective short sleep duration had HPA-associated endocrine and metabolic imbalances chronically linked to increases in cardiovascular risk observed with this more severe insomnia phenotype.

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Interactions between evening and nocturnal cortisol secretion and sleep parameters in patients with severe chronic primary insomnia

Cited by 231 publications

References 15 publications

Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy?

Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy?

The effect of working on-call on stress physiology and sleep: A systematic review

Objective short sleep duration is associated with the activity of the hypothalamic-pituitary-adrenal axis in insomnia

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