Interactions between invasive fungi and symbiotic bacteria

Wang, Fen; Xin, Caiyan; Liu, Jiexing; Ran, Zhuonan; Zhao, Chunling; Song, Zhimin

doi:10.1007/s11274-020-02913-3

Cited by 15 publications

(9 citation statements)

References 97 publications

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“…Co‐cultivation leads to interaction‐mediated induction of SM production and therefore it is used to identify potent antimicrobials synthesized by both bacteria and fungi (Dusane et al ., 2011; Imhoff et al ., 2011; Netzker et al ., 2015; Stopnisek et al ., 2016; Abdalla et al ., 2017). The reader is referred to several reviews for details on historical perspective and advanced research on drug discovery (Durand et al ., 2019; Hutchings et al ., 2019; Caesar et al ., 2020; Wang et al ., 2020). For instance, co‐cultivation of the soil‐dwelling Streptomyces rapamycinicus separately with Aspergillus nidulans and A. fumigatus activates/induces the syntheses of orsellinic acid and a novel Aspergillus SM, fumigermin, respectively, in which the latter provides ecological success to the fungus in shared habitat by reducing spore germination of the competitor bacterium (Schroeckh et al ., 2009; Konig et al ., 2013; Stroe et al ., 2020).…”

Section: Significance Of Bacterial‐fungal Ssms In Drug Discoverymentioning

confidence: 99%

Chemical signals driving bacterial–fungal interactions

Khalid

Keller

2021

Environmental Microbiology

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Microorganisms reside in diverse environmental communities where interactions become indispensable due to close physical associations. These interactions are driven by chemical communication among different microbial kingdoms, particularly between fungi and bacteria. Knowledge about these communication signals provides useful information about the nature of microbial interactions and allows predictions of community development in diverse environments. Here, we provide an update on the role of small signalling molecules in fungal-bacterial interactions with focus on agricultural and medicinal environments. This review highlights the range ofand response todiverse biochemicals produced by both kingdoms with view to harnessing their properties towards drug discovery applications.

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Section: Significance Of Bacterial‐fungal Ssms In Drug Discoverymentioning

confidence: 99%

Chemical signals driving bacterial–fungal interactions

Khalid

Keller

2021

Environmental Microbiology

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“…With the surge of research on microbial communities in various ecological environments, the interdomain relationships between different types of microbial communities has attracted great attention ( Kapitan et al, 2019 ; Wang et al, 2020 ). The association of plant bacterial and fungal communities is critical to overall microbial community structure and plant health ( Hassani et al, 2018 ), and intrigues numerous botanists and microbiologists.…”

Section: Introductionmentioning

confidence: 99%

Fungi-Bacteria Associations in Wilt Diseased Rhizosphere and Endosphere by Interdomain Ecological Network Analysis

et al. 2021

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In the plant rhizosphere and endosphere, some fungal and bacterial species regularly co-exist, however, our knowledge about their co-existence patterns is quite limited, especially during invasion by bacterial wilt pathogens. In this study, the fungal communities from soil to endophytic compartments were surveyed during an outbreak of tobacco wilt disease caused by Ralstonia solanacearum. It was found that the stem endophytic fungal community was significantly altered by pathogen invasion in terms of community diversity, structure, and composition. The associations among fungal species in the rhizosphere and endosphere infected by R. solanacearum showed more complex network structures than those of healthy plants. By integrating the bacterial dataset, associations between fungi and bacteria were inferred by Inter-Domain Ecological Network (IDEN) approach. It also revealed that infected samples, including both the rhizosphere and endosphere, had more complex interdomain networks than the corresponding healthy samples. Additionally, the bacterial wilt pathogenic Ralstonia members were identified as the keystone genus within the IDENs of both root and stem endophytic compartments. Ralstonia members was negatively correlated with the fungal genera Phoma, Gibberella, and Alternaria in infected roots, as well as Phoma, Gibberella, and Diaporthe in infected stems. This suggested that those endophytic fungi may play an important role in resisting the invasion of R. solanacearum.

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“…And the β-1,3-glucan of C. albicans can also enhance the resistance of Staphylococcus aureus in a multi-microbial bio lm environment [54] . It also found that the interactions between Aspergillus fumigatus, Cryptococcus and bacteria, could be a new direction for antifungal drugs [55] . In this study, it was found that there was a correlation between the abundance of most bacteria and fungi.…”

Section: Discussionmentioning

confidence: 99%

Analysis of sputum microbial diversity in patients with different histological types of lung cancer

Ran¹,

Liu²,

Xin³

et al. 2021

Preprint

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Background: The respiratory microbiome of lung cancer patients is different from healthy people. Finding the characteristics of microorganisms is conducive to exploring new directions for the assist in distinguishing different histological types of lung cancer. Methods: 16S rRNA sequencing and internal transcribed spacer sequencing were performed respectively on sputum samples from 8 adenocarcinomas, 10 squamous cell carcinomas, 5 small cell lung cancers, and 3 combined-small cell lung cancer patients. And then, bioinformatics analysis of their bacterial microbiome and fungal mycobiome were conducted. And the correlation between respiratory microorganisms and clinical characteristics was further analyzed.Results: The difference in species diversity of the respiratory tract microorganisms of different histological types of lung cancer is statistically significant. Moreover, smoking can increase the diversity of respiratory bacteria. Nevertheless, quitting smoking is beneficial to the transformation of the respiratory tract flora to a non-smoking state. Spearman’s correlation further showed that Fusarium was positively related to Streptococcus, Neisseria, Prevotella-7, and Veillonella, and Penicillium was positively related to Neisseria. Conclusions: Based on the differences of microorganisms among different histological types of lung cancer, deep composition characterization of lung cancer-related microorganisms and their clinical characteristics is an important advancement in understanding the role of microorganisms in lung cancer development.

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Interactions between invasive fungi and symbiotic bacteria

Cited by 15 publications

References 97 publications

Chemical signals driving bacterial–fungal interactions

Chemical signals driving bacterial–fungal interactions

Fungi-Bacteria Associations in Wilt Diseased Rhizosphere and Endosphere by Interdomain Ecological Network Analysis

Analysis of sputum microbial diversity in patients with different histological types of lung cancer

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