Interactions of novel pyrazole ligand and its transition metal complexes with CT-DNA and BSA: A combination of experimental and computational studies

Zhang, Nan; Liu, Xiang-rong; Zhao, Shunsheng; Yang, Zaiwen

doi:10.1016/j.poly.2022.116273

Cited by 7 publications

(4 citation statements)

References 52 publications

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“…7 Pyrazole azo ligand is reported to have the ability to bind to CT-DNA causing changes to CT-DNA replications, leading to the inhibition of bacterial cell and cell death. 13 This study aims to prepare a 1D coordination copperbased polymer derived from 4-(4 0 -nitrophenylhydrazono)-5-trifluoromethyl-2,4-dihydropyrazol-3-one.…”

Section: Introductionmentioning

confidence: 99%

A polymeric copper complex based on a pyrazole derivative: Synthesis, spectroscopic, X‐ray, and biological activity studies

Amin,

Diker,

Şahin

et al. 2024

Applied Organom Chemis

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A novel 1D coordination polymeric copper complex based on 4‐(4′‐nitrophenylhydrazono)‐5‐trifluoromethyl‐2,4‐dihydropyrazol‐3‐one was prepared and characterized spectroscopically and thermally and via X‐ray crystallographic investigation. The prepared copper‐based structure was proved to have a 1D coordination polymer. X‐ray studies showed that the polymeric copper complex was of octahedral geometry, the ligand acted as a bidentate ligand, and the nitro group attached to the ligand acted as a bridging group. The cytotoxic activities of the copper polymer were evaluated including against MCF‐7 cells (breast cancer cell line), HepG‐2 cells (hepatocellular carcinoma), and HCT‐116 cells (colon cancer cell line). The morphological alterations of the complex treated cells were investigated using an inverted microscope. The cell cycle and apoptosis were evaluated and reported. The copper polymer exhibited the best antitumor activity against HepG‐2 cells (35.22 ± 4.80 μM) while also causing a decline in the G2/M phase and a remarkable enhancement in the early apoptosis.

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Section: Introductionmentioning

confidence: 99%

A polymeric copper complex based on a pyrazole derivative: Synthesis, spectroscopic, X‐ray, and biological activity studies

Amin,

Diker,

Şahin

et al. 2024

Applied Organom Chemis

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“…When the filler content of conductive fillers is close to the percolation threshold (f c ), there is a sudden increase in ε', which is always accompanied by the inevitable loss. [9][10][11] Therefore, these materials cannot be considered suitable for capacitor applications due to the inevitable energy loss. Consequently, researchers are primarily focused on finding ways to trade off the contradiction between highε' and large E b , while maintaining a rather low loss in composite dielectrics.…”

Section: Introductionmentioning

confidence: 99%

Interfacial insight of core@double‐shell Mo@MoO₃@PS/PVDF composites towards prominently meliorative dielectric performances

Wang

Zhou

Chen

et al. 2023

J of Applied Polymer Sci

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Polymer dielectrics with synergistically large dielectric permittivity (ε') and breakdown strength (Eb) but prohibited loss is of crucial applications in the electronic devices and power equipment. In this study, we aim to elevate the integrated dielectric performances of molybdenum (Mo)/polyvinylidene fluoride (PVDF) by constructing a semiconducting molybdenum oxide (MoO3) shell and insulating polystyrene (PS) shell on the Mo surface through high‐temperature oxidation followed by suspension polymerization. The resulting core@double‐shell Mo@MoO3@PS particles were compounded with PVDF to achieve high ε' and Eb while minimizing the loss. The results reveal that the Mo@MoO3@PS/PVDF composites indicate simultaneously ameliorative ε' and Eb along with restrained loss owing to the existence of the MoO3@PS double‐shell, which not only prominently enhances the interfacial compatibility and interactions between fillers and PVDF, but significantly inhibits the conductivity and loss through impeding the long‐distance motion of carrier charges. The dielectric capabilities could be improved by adjusting the thickness of the PS interlayer. The Havriliak‐Negami equation was used to fit the experimental results, which showed the impact of the PS shell on the polarization mechanism and how it inhibits carrier migration. The Mo@MoO3@PS/PVDF with high ε' and Eb yet exceptionally low loss exhibit potential applications in microelectronics and electrical industries.

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“…At present, although conventional inorganic ceramic materials, such as barium titanate BaTiO 3 (BT), Ba(Zr 0.3 Ti 0.7 )O 3 (BZT), Pb(Zr 1Àx Ti x )O 3 (PZT), CaCu 3-Ti 4 O 12 (CCTO), present ultrahigh-ε. [4][5][6] However, due to inherent brittleness, high-dielectric loss and highproduction cost, it is unable to fulfill the strict demands of advanced electronic equipment. 7 Polymers have excellent flexibility, ultralow tanδ, and excellent electrical resistance when compared to inorganic ceramic materials.…”

Section: Introductionmentioning

confidence: 99%

Investigation into ameliorative dielectric properties of silicon/poly(vinylidene fluoride) composites by engineering insulating aluminum oxide shell as an interlayer

Lin,

Yin,

Zhou

et al. 2023

J of Applied Polymer Sci

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Flexible electronic materials with high‐dielectric constant (ɛ) and breakdown strength (Eb) but low loss is pursued. Encapsulation of conductive fillers with various insulating shells represents a promising strategy to inhibit dielectric loss or leakage current. In this work, aluminum oxide (Al2O3) encapsulated silicon (Si) core‐shell structured particles were prepared through a sol–gel approach, and then were incorporated with poly(vinylidene fluoride) (PVDF). The dielectric properties of PVDF composites with various fillers are investigated under varying frequencies. The findings demonstrate that a Al2O3 shell was formed outside the original Si, and that the Si@Al2O3/PVDF exhibit a high ɛ and elevated Eb but signally suppressive loss and restrained conductivity when compared with raw Si. The Al2O3 interlayer not only enhances the interface compatibility between the filler and the matrix and promotes interface polarizations, but also suppresses the loss and leakage current through preventing adjacent Si from directly contacting. The optimized dielectric performances can be achieved via tailoring the Al2O3 shell thickness. Furthermore, the theoretic fitting of experimental results by the Havriliak‐Negami equation deciphers the Al2O3 interlayer’ impact on the polarization mechanism. The resulting Si@Al2O3/PVDF composites with high ε but low loss, as well as boosted Eb, reveal potential applications in electrical systems.

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Interactions of novel pyrazole ligand and its transition metal complexes with CT-DNA and BSA: A combination of experimental and computational studies

Cited by 7 publications

References 52 publications

A polymeric copper complex based on a pyrazole derivative: Synthesis, spectroscopic, X‐ray, and biological activity studies

A polymeric copper complex based on a pyrazole derivative: Synthesis, spectroscopic, X‐ray, and biological activity studies

Interfacial insight of core@double‐shell Mo@MoO₃@PS/PVDF composites towards prominently meliorative dielectric performances

Investigation into ameliorative dielectric properties of silicon/poly(vinylidene fluoride) composites by engineering insulating aluminum oxide shell as an interlayer

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Interactions of novel pyrazole ligand and its transition metal complexes with CT-DNA and BSA: A combination of experimental and computational studies

Cited by 7 publications

References 52 publications

A polymeric copper complex based on a pyrazole derivative: Synthesis, spectroscopic, X‐ray, and biological activity studies

A polymeric copper complex based on a pyrazole derivative: Synthesis, spectroscopic, X‐ray, and biological activity studies

Interfacial insight of core@double‐shell Mo@MoO3@PS/PVDF composites towards prominently meliorative dielectric performances

Investigation into ameliorative dielectric properties of silicon/poly(vinylidene fluoride) composites by engineering insulating aluminum oxide shell as an interlayer

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Interfacial insight of core@double‐shell Mo@MoO₃@PS/PVDF composites towards prominently meliorative dielectric performances