Interactions of the myxothiazol and mucidin toxophores with cytochrome b

Wiggins, Thomas E.

doi:10.1042/bst021002s

Biochemical Society Transactions

1993

DOI: 10.1042/bst021002s

|View full text |Cite

Interactions of the myxothiazol and mucidin toxophores with cytochrome b

Thomas E. Wiggins¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1993

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Random mutant generation and its utility in uncovering structural and functional features of cytochromeb inSaccharomyces cerevisiae

Colson

1993

J Bioenerg Biomembr

View full text Add to dashboard Cite

The generation of random mutations in the mitochondrial cytochrome b gene of Saccharomyces cerevisiae has been used as a most fruitful means of identifying subregions that play a key role in the bc1 complex mechanism, best explained by the protonmotive Q cycle originally proposed by Peter Mitchell. Selection for center i and center o inhibitor resistance mutants, in particular, has yielded much information. The combined approaches of genetics and structural predictions have led to a two-dimensional folding model for cytochrome b that is most compatible with current knowledge of the protonmotive Q cycle. A three-dimensional model is emerging from studies of distant reversions of deficient mutants. Finally, interactions between cytochrome b and the other subunits of the bc1 complex, such as the iron-sulfur protein, can be affected by a single amino acid change.

show abstract

Random mutant generation and its utility in uncovering structural and functional features of cytochromeb inSaccharomyces cerevisiae

Colson

1993

J Bioenerg Biomembr

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Interactions of the myxothiazol and mucidin toxophores with cytochrome b

Cited by 1 publication

References 4 publications

Random mutant generation and its utility in uncovering structural and functional features of cytochromeb inSaccharomyces cerevisiae

Random mutant generation and its utility in uncovering structural and functional features of cytochromeb inSaccharomyces cerevisiae

Contact Info

Product

Resources

About