Interactive effects of naphthalene treatment and the onset of vitellogenesis on energy metabolism in liver and gonad, and plasma steroid hormones of rainbow trout Oncorhynchus mykiss

Can Naphthalene Exposure Stress Alter Brain Biogenic Amine Levels Before and during Vitellogenesis in Liza klunzingeri Fish?

“…The results of the present research showed a significant decrease of 17β-estradiol levels at both previtellogenic and vitellogenic stages after the long-term NAP stress. Similar findings are reported on the effects of beta-naphthoflaven on Coho salmon [28] and BaP on Flander fish [9], rainbow trout [1] and Atlantic croaker [4]. PAHs are lipophilic compounds that may be stored in the tissues enriched in lipids, e.g., gonads and brain; therefore, they can have many effects on these organs [29,30].…”

“…Generation requires a successful reproduction in living organisms. In mature ovaries of female fish vitellogenesis is an important physiological process during which ova store yolk [1]. This process is started by gonadotropin hormones released from pituitary into the blood stream.…”

Steroid catabolism in marine and freshwater fish

“…These studies suggest that UGTs, particularly those that catalyze steroid glucuronidation, can be induced but are not as sensitive to induction by planar polycyclic aromatic compounds as the P450 isoforms in the CYP1 family. Studies have shown that exposure to polycyclic aromatic hydrocarbons is associated with altered steroid levels in fish [76,77], and it is possible that changes in the content and activity of steroid-metabolizing UGT could contribute to the observed effects, however further studies are needed to draw this conclusion.…”

Endocrine-Disrupting Chemicals and Oil and Natural Gas Operations: Potential Environmental Contamination and Recommendations to Assess Complex Environmental Mixtures

“…Many of these chemicals have documented adverse health effects in humans, are designated priority pollutants by the U.S. EPA, and/or are known or suspected EDCs ( Colborn et al 2011 ; Waxman et al 2011 ). For example, exposure to naphthalene, a constituent of crude oil and a chemical used by industry for hydraulic fracturing processes ( Waxman et al 2011 ) and that has been reported in air and water near operations ( Colborn et al 2014 ; DiGiulio et al 2011 ; Wolf Eagle Environmental 2009 ), can result in altered steroid hormone levels, increased reproductive abnormalities, and impaired sexual maturation in animal models and in vitro ( Hansen et al 2008 ; Pollino et al 2009 ; Thomas and Budiantara 1995 ; Tintos et al 2006 ), albeit generally at greater concentrations than those reported near these sites.…”