Most business services based on Ubiquitous Computing are being designed with a sole focus on the technological sector, without considering business elements. In light of this trend, this study was intended to design a user-oriented u-Business service for preventing and promptly responding to industrial disasters at shipbuilding sites using a systematic methodology. Specifically, major danger elements of disasters in need of preferential preventive and responsive measures were derived as business opportunities unfulfilled by the current process, and then a u-Business service was developed to prevent/respond to such dangers. Statistical analysis was performed on the developed services according to evaluation models, and the final u-Business service was selected based on this analysis. Resources and information systems were designed to support the chosen service.