Interactive real-time computation

Reflex control of heart rate in the unanesthetized dog

“…from this laboratory (14) concerned the effects of changes in carotid sinus pressure on the peripheral resistance in the anesthetized cat and dog. It produced a semiquantitative description of that relationship which has since been corroborated (9). In that study, the time constants of the response were relatively unchanging, but the "gain" constants exhibited a wide variability, and the amount of control exerted by the reflex at times appeared surprisingly low.…”

“…Correlation between recorded and predicted intervals range from .86 to .95 (Figs. 6,7,and 9) K2 is between .003 and .04 for animals without anesthesia and lower with any anesthetic. The correlation is not improved by a time delay unless the heart rate is greater than 120.…”

“…der responses to inflation of the as-Res-onses to descending cu$ vagal response (9). At normal "vagal" heart rates in the awake animal, we do not need to consider complicated differential equations.…”