Intercalation Lithium Cobalt Oxide for the Facile Fabrication of a Sensitive Dopamine Sensor

Abstract

Intercalation lithium cobalt oxide (LCO) with the properties of insertion and de‐intercalation of Li+ was utilized to fabricate the sensitive dopamine (DA) sensor, which has excellent adsorption and catalytic behavior. LCO mixed with graphite powder (LCO−G) for individual and simultaneous determination of DA and uric acid (UA) achieved the low detection limits and the wide concentration ranges without the interference of ascorbic acid (AA). For individual detection, the linear responses of DA and UA were in the concentration ranges of 0.020–20 μM and 0.500–200 μM with the detection limits of 4.0 nM and 0.18 μM (s/n=3), respectively. For simultaneous detection with UA and AA by the change of the concentrations of DA, the linear response ranges were 0.050–20 μM with the detection limit of 7.9 nM (s/n=3). The LCO−G/GCE was further applied to the detection of DA in human serum to illustrate its potential of highly sensitive and selective electrochemical sensing.

Defective Prussian Blue Analogue with Cobalt for Fabrication of An Electrochemical Sensor for Detecting Ascorbic Acid, Dopamine and Uric Acid

“…are the most commercially successful form of cathodic materials [3] . Not only being outstanding in the fabrication of energy storage devices, some of the Li‐ion battery materials can be further utilized for the fabrication of electrochemical sensors benefit from their stable framework and intrinsic transition metal atoms with catalytic behavior toward some electroactive species [4,5] . However, the limited lithium reserves on Earth and high cost might hinder the large‐scale application in both of energy storage and electrochemical sensing.…”

“…[3] Not only being outstanding in the fabrication of energy storage devices, some of the Li-ion battery materials can be further utilized for the fabrication of electrochemical sensors benefit from their stable framework and intrinsic transition metal atoms with catalytic behavior toward some electroactive species. [4,5] However, the limited lithium reserves on Earth and high cost might hinder the large-scale application in both of energy storage and electrochemical sensing. In pursuit of affordable electric storage batteries for large-scale electric energy storage applications, Naion batteries appear to be an attractive alternative to their lithium counterparts because of the natural abundance and low cost of Na resource.…”