Intercalation of Ga3+-salicylidene-amino acid Schiff base complexes into layered double hydroxides: Synthesis, characterization, acid resistant property, in vitro release kinetics and antimicrobial activity

Antimicrobial activity of 2-mercaptobenzothiazole released from environmentally friendly nanostructured layered double hydroxides

“…The addition of LDH without the biocide did not affect light emission, indicating that this material is not toxic per se. Similar results pointing to the negligible toxicity of LDH against Gram-positive and Gram-negative bacteria have already been reported (Ryu et al 2010;Wang et al 2013). Therefore, LDHs can be regarded as biologically compatible materials.…”

Two‐Dimensional Materials for Antimicrobial Applications: Graphene Materials and Beyond

“…Because of this fascinating feature, along with good biodegradability,c omposition-dependent properties, and easy preparation, LDHs have becomea ni deal reservoir for sustained and controlled drug release. In general, low-molecularweighta ntimicrobial agents (listed in Table 2) and metal (Ga 3 + ) complexes [142] have been successfully insertedi nto the basal space of LDHs. Continuous and slow drug releasei sa chieved by LDH-small molecule nanocomposites,w hich circumvents the toxicitythat may arise from burst leakage of drugs.Inaddition, some antimicrobial agents becomeb iologically inactive when exposed to sources of light or heat;h owever,a fter they are intercalated into LDHs, their chemicals tability/photostability can be improved.…”

Inorganic nanolayers: structure, preparation, and biomedical applications

“…138 The designed nanocomposites retained antimicrobial activity against P. aeruginosa, with a very good minimum inhibitory concentration (65-137 μmol⋅L −1 ). 138 Many different antimicrobial agents, eg, amoxicillin 139 and cefazolin, 140 have been successfully intercalated into LDHs.…”