Interchanging Scores Between Clinical Dementia Rating Scale and Global Deterioration Scale

Choi, Seong Hye; Lee, Byung Hwa; Kim, Seonwoo; Hahm, Dong Seok; Jeong, Jee Hyang; Yoon, Soo Jin; Jeong, Yoong Ki; Ha, Choong Keun; Nab, Duk L.

doi:10.1097/00002093-200304000-00008

Cited by 53 publications

(39 citation statements)

References 14 publications

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“…Eligible patients were 50-85 years of age and had a diagnosis of aMCI according to the operationalized Petersen criteria [1], which included the following: a subjective memory complaint that was corroborated by an informant; objective memory decline, as defined by a delayed recall score of the Seoul Verbal Learning test worse than 1.0 standard deviations (SD) below age- and education-adjusted normative means [15]; normal general cognitive function, as defined by the Clinical Dementia Rating (CDR) scale of 0.5 [16], and a Mini-Mental State Examination (MMSE) score of more than 1.5 SD below age- and education-adjusted normative means [17]; preserved activities of daily living (ADL), as defined by Seoul Instrumental ADL ≤7 [18], and a lack of dementia. All subjects had a Hachinski Ischemic Score ≤4 [19], brain MRI or CT showing no other diseases capable of producing cognitive impairment and a reliable informant who met the subject at least once a week and was sufficiently familiar with him/her to provide the investigator with accurate information.…”

Section: Methodsmentioning

confidence: 99%

“…The primary efficacy outcome was the change from baseline to PI in the modified AD Assessment Scale-cognitive subscale (ADAS-Cog, range 0-89) [25]. Secondary outcome measures included the MMSE (range 0-30) [17], Digit Symbol Coding test (range 0-90), Stroop test (range 0-112), Animal Fluency, Controlled Oral Word Association Test (COWAT), story recall test [20], Forward Digit Span test (range 0-9), Backward Digit Span test (range 0-8), CDR-Sum of Boxes (CDR-SB, range 0-18) [16], 15-item version of the Geriatric Depression Scale (GDS-15, range 0-15) [26], Caregiver-Administered Neuropsychiatric Inventory (CGA-NPI, range 0-144) [27], Bayer ADL (range 1-10) [28], Prospective and Retrospective Memory Questionnaire (PRMQ, range 16-80) [29,30], AD8 (range 0-8) [31], Prospective Memory Test (PMT, range 0-12) modified from the Royal Prince Alfred PMT [32], QOL-AD (range 0-52) [33] and Multifactorial Metamemory Questionnaire (MMQ)-Strategy subscale (range 0-76) [22,34]. The PMT consisted of four tests regarding short- and long-term, and event- and time-based prospective memory.…”

Section: Methodsmentioning

confidence: 99%

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Group- and Home-Based Cognitive Intervention for Patients with Mild Cognitive Impairment: A Randomized Controlled Trial

Jeong

Choi

et al. 2016

Psychother Psychosom

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Background: We examined the efficacy of group-based cognitive intervention (GCI) and home-based cognitive intervention (HCI) in amnestic mild cognitive impairment (aMCI) and intervention effects on serum brain-derived neurotrophic factor (BDNF). Methods: In this randomized and rater-blinded trial, 293 patients with aMCI from 18 nationwide hospitals were randomized: 96 to the GCI group, 98 to the HCI group and 99 to the control group. For 12 weeks, subjects receiving GCI participated twice per week in group sessions led by trained instructors, and those receiving HCI completed homework materials 5 days per week. They were assessed at baseline, postintervention (PI) and at the 6-month follow-up after the intervention. The primary endpoint was the change from baseline to PI in the modified Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-Cog). Results: In comparison to the controls (a 0.8-point decrease), the subjects receiving GCI (a 2.3-point decrease, p = 0.01) or HCI (a 2.5-point decrease, p = 0.02) showed significant improvements in the modified ADAS-Cog at PI, respectively. By the 6-month follow-up, those receiving GCI or HCI had better scores in the modified ADAS-Cog than the controls. The changes in BDNF levels significantly correlated with the changes in the modified ADAS-Cog in the GCI (r = -0.29, p = 0.02 at PI) and HCI (r = -0.27, p = 0.03 at 6-month follow-up) groups, respectively. Conclusions: The GCI and HCI resulted in cognitive improvements in aMCI. An enhanced brain plasticity may be a component of the mechanism underpinning the cognitive improvements associated with the cognitive interventions.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Group- and Home-Based Cognitive Intervention for Patients with Mild Cognitive Impairment: A Randomized Controlled Trial

Jeong

Choi

et al. 2016

Psychother Psychosom

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“…Some studies only included individuals with a specific level of severity, others included individuals with a range of severity levels; the most common selection was individuals across the spectrum of mild to severe dementia (n=4). When determining the severity, tools such as the Clinical Dementia Rating and the Global Deterioration Scale should be used as they assess multiple aspects of dementia: cognition, emotion, memory and functional ability (29) ; both scale were used in one study each (20,21) . Often, cognitive screening tools such as the Mini Mental State Examination (MMSE) are used to determine severity of dementia, and in this review it was the most commonly used approach to assessing severity of dementia (n=10).…”

Section: Participant Characteristics and Sample Sizementioning

confidence: 99%

“…Often, cognitive screening tools such as the Mini Mental State Examination (MMSE) are used to determine severity of dementia, and in this review it was the most commonly used approach to assessing severity of dementia (n=10). This tool is limited because it only assesses one element of dementia and is influenced by the educational level of an individual (29) . Due to the variation of tools used and the different aspects of dementia assessed, it was not possible to compare the effects of physical exercise on the severity of dementia across the studies.…”

Section: Participant Characteristics and Sample Sizementioning

confidence: 99%

Effects of Physical Exercise on Health and Well-Being of Individuals Living With a Dementia in Nursing Homes: A Systematic Review

Brett

Traynor

Stapley

2016

Journal of the American Medical Directors Association

152

135

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Background Physical exercise interventions have benefits for older individuals and improve the health and well-being of individuals living with a dementia, specifically those living in nursing homes. Purpose Report evidence from randomized controlled trials and cluster randomized control trials that evaluated the effects of physical exercise interventions on individuals living with a dementia in nursing homes. Data sources Web of Science, Scopus, Science Direct, Academic Search Complete, Proquest Central, British Medical Journal Database, PubMed, Cochrane Library, PEDro, Informit, Informa, and Nursing Consult were searched for relevant clinical trials and snowballing of recommended studies. Study selection One reviewer screened articles on inclusion criteria and identified relevant studies. Data extraction Data extraction was performed by 1 reviewer and checked by second and third reviewers. Two authors assessed the methodological quality and risk of bias of the relevant studies. Data synthesis Twelve study populations consisting of individuals living with a dementia in nursing homes were included (n = 901). Different types of physical exercises were undertaken: multimodal (n = 6), walking (n = 5), music and movement (n = 2), and hand exercises (n = 1). The parameters of the interventions varied across the studies. Most of the studies reported significant positive effects of physical exercise on cognition, agitation, mood, mobility, and functional ability for individuals living with dementia in nursing homes. Limitations The main limitations were the heterogeneity of design, small samples, and short interventions. Conclusions There is emerging evidence that physical exercise significantly benefits individuals living with a dementia in nursing homes. Higher quality research is required adopting more rigorous methods, including longer interventions and larger samples to determine optimum parameters of the physical exercise interventions evaluated.

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“…Son muy escasos los estudios que buscan esta correlación; así Choi et al (29), realizan un estudio de intercambio de puntaje entre CDR y GDS y encuentran una correlación casi perfecta entre ambas escalas, de 0,97 para todos los sujetos, y de 0,97 y 0,96 para los subgrupos de sujetos sin demencia y enfermedad de Alzheimer y sujetos sin demencia y demencia vascular, respectivamente. Encontramos igualmente una correlación casi perfecta (0,97) para todos los casos de demencia, coincidiendo con estos autores.…”

Section: Discussionunclassified

Validación y precisión de la escala de deterioro global (GDS) para establecer severidad de demencia en una población de Lima

Custodio

Becerra-Becerra

Alva-Díaz

et al. 2017

CES Med

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Artículo de investigación Validación y precisión de la escala de deterioro global (GDS) para establecer severidad de demencia en una población de LimaValidation and diagnostic accuracy of the Global Deterioration Scale (GDS) ResumenObjetivo: validar y evaluar el rendimiento de la Global Deterioration Scale (GDS) en una población que acude a una unidad especializada de Lima. Pacientes y métodos: investigación de tipo transversal con un diseño descriptivo comparativo. El estudio incluyó 215 individuos seleccionados de forma abierta, que acudieron a la unidad de diagnóstico de deterioro cognitivo y prevención de demencia. Se estudiaron tres grupos: 60 controles, 40 con diagnóstico de deterioro cognitivo leve y 115 con demencia. Los individuos fueron sometidos a evaluaciones sucesivas: cribado, diagnóstico y estadiaje de demencia y tipo de demencia. La validez y fiabilidad de la clasificación de severidad fue demostrada mediante la concordancia entre la medición del Global Deterioration Scale con el Clinical Dementia Rating (CDR). El rendimiento de Global Deterioration Scale se valoró mediante la obtención de los valores de sensibilidad y especificidad. Resultados: los promedios de edad fueron de 69, 70, y 74 años para los controles, los pacientes con deterioro cognitivo leve y los pacientes con demencia, respectivamente. La Global Deterioration Scale tuvo una buena correlación con Clinical Dementia Rating (r de Spearman =0,97; P=0,0001). La sensibilidad de la escala para establecer estadio de demencia fue de 79 %, con especificidad del 100 % para cualquier categoría de demencia según los criterios diagnósticos estándares y según Clinical Dementia Rating. Conclusiones: se encontró una correlación casi perfecta entre Global Deterioration Scale y Clinical Dementia Rating; sin embargo, la Global Deterioration Scale presenta una sensibilidad moderada para establecer el estadio de demencia con respecto a Clinical Dementia Rating, mostrando además ser utilidad en el diagnóstico de deterioro cognitivo leve.Palabras clave: Global Deterioration Scale, Clinical Dementia Rating, Demencia, Escalas de estadiaje clínico de demencia. AbstractObjective: To validate and evaluate diagnostic accuracy of the Global Deterioration Scale (GDS) in a population of a specialized unit of Lima. Patients Comparte MEDICINACustodio N, Becerra-Becerra Yc, Alva-Diaz C, Montesinos R , Lira D, Herrera-Pérez E. Enero -Junio 2017 -Pág 15and Methods: This research is a comparative cross-sectional descriptive design. The study included 215 individuals selected openly, who attending in the diagnostic unit of cognitive impairment and dementia prevention. Three groups were studied: 60 controls, 40 individuals diagnosed with mild cognitive impairment (MCI) and 115 with dementia diagnosis. They were assessments in three phases: screening, diagnosis and staging of dementia and type of dementia. The validity and reliability of the classification of severity was demonstrated by measuring the correlation between the GDS with the CDR (Clinical Dementia Rating)....

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Interchanging Scores Between Clinical Dementia Rating Scale and Global Deterioration Scale

Cited by 53 publications

References 14 publications

Group- and Home-Based Cognitive Intervention for Patients with Mild Cognitive Impairment: A Randomized Controlled Trial

Group- and Home-Based Cognitive Intervention for Patients with Mild Cognitive Impairment: A Randomized Controlled Trial

Effects of Physical Exercise on Health and Well-Being of Individuals Living With a Dementia in Nursing Homes: A Systematic Review

Validación y precisión de la escala de deterioro global (GDS) para establecer severidad de demencia en una población de Lima

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