“…Thoracoscopy has been suggested as the technique of choice for ectopic glands located to the middle and lower mediastinal regions; some limitations have been reported in case of immediately retrosternal parathyroids in the upper part of the anterior mediastinum, with an increased risk of convertion [3,6,8,22,23]. However, thoracoscopic approach may be laborious; it requires single-lung ventilation, pleural incision, and cannot be safely performed in patients with compromised pulmonary function or chest adhesions [20,21]. To the contrary, video-assisted transcervical approaches may be still less invasive, since the selective single-lung ventilation may be avoided; surgery may be performed with the patient in classic supine position with a comfortable incision, without violation of the pleural space [34]; operative time are comparable to thoracoscopic procedures [20], while some difficulties have been reported to excise deep glands in the posterior mediastinum [6,13,21].…”