Interfacing a microfluidic electrophoresis chip with inductively coupled plasma mass spectrometry for rapid elemental speciation

Song, Qi; Greenway, Gillian M.; McCreedy, Tom

doi:10.1039/b401657b

Cited by 55 publications

(36 citation statements)

References 25 publications

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“…Finally, the analytical potential of CE-ICP-MS technique with the selected applications in this field (from 2002 to June 2004) to tackle trace-elementspeciation problems is discussed by Alvarez-Llamas et al [6]. More recently, new methods and applications have been proposed for a range of chemical forms of metals [66,69,200], arsenic [67,73,201,202], selenium [74,201], mercury [24], manganese [71], and iodophenols [68]. Some examples will be briefly described below.…”

Section: Speciationmentioning

confidence: 97%

“…Various detection methods such as fluorescence spectrometry [122], conductivity [123,124], PAD [39], MS [125], and ICP-MS [64,66] were utilized. However, this technique is still away from being routinely applied and, therefore, most papers deal with the possibility of chipbased CE itself rather than validated application to the real-world sample.…”

Section: Separation On Microchipsmentioning

confidence: 99%

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Recent advances in capillary electrophoresis and capillary electrochromatography of pollutants

Da̧bek-Złotorzyńska

Celo

2006

Electrophoresis

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Section: Speciationmentioning

confidence: 97%

Section: Separation On Microchipsmentioning

confidence: 99%

Recent advances in capillary electrophoresis and capillary electrochromatography of pollutants

Da̧bek-Złotorzyńska

Celo

2006

Electrophoresis

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“…The detection limits for As(III) and As(V) are 3.9 and 5.4 ng·mL , at the moment the microchip system requires manual filling with background buffer and sample. Further improvements of the features of μCE-HG-MIP-OES may lie in the use of aminiaturized MIP at atmospheric pressure and miniaturized and portable spectrometer because toxic of hevy metal As(V) is much higher than that of As(III) [138,139]. There are few proposed methods to the direct determination of As(V), without pretreatment of samples.…”

Section: Determination Of Mercurymentioning

confidence: 99%

A Review of the Potential Issues of Pollution Caused by the Mineral Elements, Mercury, Lead and Arsenic, Its Possible Impacts on the Human Beings and the Suggested Solutions

Lam¹,

Sze²,

Yao³

et al. 2012

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Objective: This paper mainly discusses and summarises the potential issues of pollution caused by the Mineral elements, Mercury, Lead and Arsenic, its possible impacts on the human beings and the suggested solutions. Methods: This paper is prepared by reviewing the latest academic literatures. Result: First, this article discusses two aspects including the effects of Mercury, Lead and Arsenic on the Chinese herbal medicine and the potential issues of causing the environmental pollution. And then further study its toxicity effects and the side impacts on the human bodies in order to realize the actual circumstances people are encountering nowadays. This paper will also the corresponding its treatment method of reviews. Hope this will provide a valuable reference. Conclusion: Theses issues caused by the Mineral elements are prominent nowadays, thus the ongoing researches on the impacts of pollution and the possible solutions are regarded as highly valued in order to conserve the natural environment and meanwhile safeguard the well beings of people and the future offspring.

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“…Besides its great advantages, the reduced dimensions of the chip resulted in detection problems. The small volumes (typically , nL) encountered in most chip-CE systems have led to the development of a diversity of detection methods that provide high sensitivity and low detection limits [7][8][9][10][11][12][13][14][15][16][17][18][19]. Due to the short optical length, the detection methodology via absorbance commonly used in HPLC and conventional CE was not suitable [7].…”

mentioning

confidence: 98%

Development of a new hybrid technique for rapid speciation analysis by directly interfacing a microfluidic chip-based capillary electrophoresis system to atomic fluorescence spectrometry

Wang

Yan

et al. 2005

Electrophoresis

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This paper represents the first study on direct interfacing of microfluidic chip-based capillary electrophoresis (chip-CE) to a sensitive and selective detector, atomic fluorescence spectrometry (AFS) for rapid speciation analysis. A volatile species generation technique was employed to convert the analytes from the chip-CE effluent into their respective volatile species. To facilitate the chip-CE effluent delivery and to provide the necessary medium for subsequent volatile species generation, diluted HCl solution was introduced on the chip as the makeup solution. The chip-CE-AFS interface was constructed on the basis of a concentric "tube-in-tube" design for introducing a KBH4 solution around the chip effluent as sheath flow and reductant for volatile species generation as well. The generated volatile species resulting from the reaction of the chip-CE effluent and the sheath flow were separated from the reaction mixture in a gas-liquid separator and swept into the AFS atomizer by an argon flow for AFS determination. Inorganic mercury (Hg(II)) and methylmercury (MeHg(I)) were chosen as the targets to demonstrate the performance of the present technique. Both mercury species were separated as their cysteine complexes within 64 s. The precision (relative standard deviation, RSD, n = 5) of migration time, peak area, and peak height for 2 mg.L(-1) Hg(II) and 4 mg.L(-1) MeHg(I) (as Hg) ranged from 0.7 to 0.9%, 2.1 to 2.9%, and 1.5 to 1.8%, respectively. The detection limit was 53 and 161 microg.L(-1) (as Hg) for Hg(II) and MeHg(I), respectively. The recoveries of the spikes of mercury species in four locally collected water samples ranged from 92 to 108%.

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Interfacing a microfluidic electrophoresis chip with inductively coupled plasma mass spectrometry for rapid elemental speciation

Cited by 55 publications

References 25 publications

Recent advances in capillary electrophoresis and capillary electrochromatography of pollutants

Recent advances in capillary electrophoresis and capillary electrochromatography of pollutants

A Review of the Potential Issues of Pollution Caused by the Mineral Elements, Mercury, Lead and Arsenic, Its Possible Impacts on the Human Beings and the Suggested Solutions

Development of a new hybrid technique for rapid speciation analysis by directly interfacing a microfluidic chip-based capillary electrophoresis system to atomic fluorescence spectrometry

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