Interferência da idade sobre a qualidade seminal

Abstract

XLSTAT (p<0,05). RESULTADOS: os indivíduos estudados tinham média de idade de 37±7,9 anos, com um volume seminal médio de 3±1,4 mL, uma concentração espermática de 61,4±66,4 espermatozóides por mL de sêmen, motilidade progressiva de 44,7±19,4% do total de espermatozóides e morfologia normal de 11,2±6,6% dos espermatozóides. As médias de idade entre os grupos foram semelhantes, exceto a média dos indivíduos com hipoespermia, que foi significativamente maior que a dos homens com normoespermia (39,6±10,3 versus 36,5±7,3, p=0,001). CONCLUSÕES: a idade interfere, de forma inversamente proporcional, sobre o volume do ejaculado, porém não exerce influência na concentração, motilidade e morfologia espermática.Abstract PURPOSE: to evaluate the influence of age on the quality of semen in men submitted to spermatic analysis in a human reproduction service, in cases of conjugal infertility. METHODS: a retrospective study in which the spermiograms of all men in process of investigation for conjugal infertility in a service of assisted reproduction in the Northeast of Brazil were evaluated from September 2002 to December 2004. A number of 531 individuals submitted to 531 spermatic evaluations were included in the study. The following parameters have been analyzed: spermatic volume, concentration, motility and morphology. The men under investigation have been divided in groups, according to the results obtained in each of the variables studied. Seminal volume groups were divided in: hypospermia, normospermia and hyperspermia. Spermatic concentration groups were divided in: azoospermia, oligospermia, normospermia and polyspermia. Motility groups were divided in: normal motility and asthenospermia. Morphology groups were divided in: normal morphology and teratospermia. The t test has been used to compare the average age of patients in groups with normal and in groups with altered parameters. The program XLSTAT (p<0.05) has been used for the statistical analysis. RESULTS: the individuals studied presented an average of 37±7.9 years old, with an average of seminal volume of 3±1.4 mL, a spermatic concentration of 61.4±66.4 spermatozoids by mL of semen, a progressive motility of 44.7±19.4% of the total of spermatozoids and normal morphology of 11.2±6.6% of the spermatozoids.

A Comprehensive and Systematic Study of Semen Quality and Sperm Functional Status in Normozoospermic Controls and Infertile Males from South India

“…Berling and Wolner-Hanssen (1997) study that analysed 718 infertile Swedish men for a period of 10 years reports insignificant decrease in semen volume and increase in morphology and motility, thereby fails to establish a correlation between age and semen parameters [43]. A most recent study showed an inverse effect of age on semen volume, but not on other semen parameters [42]. This ambiguous relationship between age and changes in semen features are also observed in our study subjects.…”

“…Several reports demonstrated the inverse relationship between age and the semen parameters [33,35], on contrary other studies showed the negligible influence of age on various semen characteristics [34][35][36]42]. For example, Kidd et al, (2001) suggested that advanced age is associated with a decrease in semen volume, sperm motility, and sperm morphology, but has no effect on sperm count [30].…”

Study of Variables Involved in Male Infertility Identified in the Spermograms Assessed in Assisted Human Reproduction

“…A recent review has found it difficult to find in the literature a clear relationship between increased paternal age and sperm concentration 24 . Azoospermic individuals were older than normozoospermic ones, however, when compared, the average ages did not present significant differences 25 . However, in the present analysis, the azoospermia group had a significantly higher average age than the normozoospermia group, suggesting a decrease in concentration with increasing age.…”

Influence of age on sperm parameters in men with suspected infertility

“…There are many studies that focus on the correlation between age and male / female infertility, all of them concluding that advanced paternal age is a strong risk factor of disorders that include production and sperm quality (CAVALCANTE et al 2008, [5]). Although there is no age limit for male fertility, studies reveal that fertility starts to decline at the age of 40 (TELÕKEN et al 1999, [33]).…”

“…(AITKEN et al 1995, [3]; PASQUALOTTO et al 2011, [4]). Factors such as urogenital infections, exposure to toxic substances and vascular diseases may impair seminal quality, resulting in embryonic defects, loss of pregnancy or children highly prone to develop genetic diseases and other pathologies (CAVALCANTE et al 2008, [5]). The correct estimation of male fertility potential has become of great interest to researchers, but available tests are not always accurate for this specific pathology.…”