2020
DOI: 10.21203/rs.3.rs-64010/v1
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Interferon-based therapy did not attenuate hepatitis C-associated rheumatic disorder risk: A nationwide population-based cohort study

Abstract: BackgroundWhether hepatitis C virus (HCV) infection increases the risk of rheumatic disorders and whether the associated risk is reversed by anti-HCV therapy remain elusive. We aimed to investigate these topics. MethodsA nationwide population-based cohort study of Taiwan National Health Insurance Research Database (TNHIRD) was conducted. ResultsOf 19,298,735 subjects, 3 TNHIRD cohorts (1:4:4, propensity score-matched), including HCV-treated (6,919 HCV-infected subjects with interferon and ribavirin therapy >… Show more

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“…HCV is typically transmitted through substantial or recurrent contact with blood, such as transfusion [121]. It was found to be primarily associated with liver-related issues like cirrhosis and could also lead to complications beyond the liver, such as diabetes mellitus [122]. As for its association with GC, current research has not established a direct link between HCV infection and the development of GC.…”
Section: Infection Of Hbv and Hcvmentioning
confidence: 99%
“…HCV is typically transmitted through substantial or recurrent contact with blood, such as transfusion [121]. It was found to be primarily associated with liver-related issues like cirrhosis and could also lead to complications beyond the liver, such as diabetes mellitus [122]. As for its association with GC, current research has not established a direct link between HCV infection and the development of GC.…”
Section: Infection Of Hbv and Hcvmentioning
confidence: 99%