Interferon lambda receptor-1 isoforms differentially influence gene expression and HBV replication in stem cell-derived hepatocytes

Novotny, Laura A.; Evans, J. Grayson; Guo, Haitao; Kappler, Christiana S.; Meissner, Eric G.

doi:10.1016/j.antiviral.2023.105779

Antiviral Research

2024

DOI: 10.1016/j.antiviral.2023.105779

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Interferon lambda receptor-1 isoforms differentially influence gene expression and HBV replication in stem cell-derived hepatocytes

Laura A. Novotny,

J. Grayson Evans,

Haitao Guo

et al.

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2024

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Cited by 2 publications

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Expression and function of interferon lambda receptor 1 variants

Novotny,

Meissner

2024

FEBS Letters

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Lambda interferons (IFNLs) provide critical host defense against pathogens encountered at mucosal surfaces. In humans, IFNL signaling is regulated in part by low and cell‐type restricted expression of the lambda interferon receptor 1 protein with expression restricted primarily to epithelial cells located at mucosal surfaces. This review will examine the evidence suggesting a role for IFNLR1 transcriptional variants in mediating cell responsiveness to IFNL ligand exposure and regulation of pathway activity.

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Expression and function of interferon lambda receptor 1 variants

Novotny,

Meissner

2024

FEBS Letters

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show abstract

Molecular characteristics of rhesus macaque interferon-lambda receptor 1 (mmuIFNLR1): Sequence identity, distribution and alteration after simian-human immunodeficiency virus infection in the skin and buccal mucosa

Liu,

Yang

2024

Developmental & Comparative Immunology

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Interferon lambda receptor-1 isoforms differentially influence gene expression and HBV replication in stem cell-derived hepatocytes

Cited by 2 publications

References 60 publications

Expression and function of interferon lambda receptor 1 variants

Expression and function of interferon lambda receptor 1 variants

Molecular characteristics of rhesus macaque interferon-lambda receptor 1 (mmuIFNLR1): Sequence identity, distribution and alteration after simian-human immunodeficiency virus infection in the skin and buccal mucosa

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