Interim Guidelines for the Evaluation and Testing of Infants with Possible Congenital Zika Virus Infection — United States, 2016

Zika virus disease: a current review of the literature

“…The infected child and the family should be counseled by a multidisciplinary team consisting of clinical geneticists or dysmorphologists, pediatric neurologists, pharmacists, infectious disease specialists and other related specialists [98]. Long-term follow-up should also be offered to monitor functional, physical and intellectual progress of the child [98].…”

“…Long-term follow-up should also be offered to monitor functional, physical and intellectual progress of the child [98].…”

“…Travelers to or residents in the affected areas should spend maximum time indoor or use insect repellents while going outdoors. They should also use full sleeve shirts, long pants and if possible permethrin-treated clothes [98]. Registered insect repellents, including DEET, should be prepared in such concentrations that are safe for pregnant and lactating women (20 % DEET), and children (10 % DEET) aged >2 months [99].…”

Update: Interim Guidelines for Health Care Providers Caring for Pregnant Women and Women of Reproductive Age with Possible Zika Virus Exposure — United States, 2016

“…Testing is recommended at the time of delivery, including histopathologic examination of the placenta and umbilical cord, testing of frozen placental tissue and cord tissue for Zika virus RNA, and testing of cord serum (1,19). Guidelines for infants whose mothers have possible Zika virus infection are available (19). If a pregnant woman with Zika virus disease experiences a fetal loss, Zika virus RT-PCR and immunohistochemical staining should be performed on fetal tissues, including umbilical cord and placenta (1).…”

Zika Virus —10 Public Health Achievements in 2016 and Future Priorities

“…CDC's first Zika-related clinical guidance outlining evaluation, testing, and clinical management of Zika virus in pregnant women was released on January 19, 2016 (6), and on January 26, 2016, guidance for the evaluation and testing of infants with possible congenital Zika virus infection was released (7). As new evidence emerged, CDC updated pregnancy and infant guidance and developed guidance for reproductive-aged women (8)(9)(10)(11)(12)(13).…”