2020
DOI: 10.21203/rs.2.18910/v2
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Interim PET/CT Result Is The Sole Prognostic Factor Of Survival In Patients With Advanced-Stage Diffuse Large B-cell Lymphoma:A Prospective Trial

Abstract: Background: We assessed whether interim positron emission tomography (iPET) had a prognostic value for diffuse large B-cell lymphoma (DLBCL) and whether PET-driven intensified therapy was needed. Methods: A prospective analysis of newly diagnosed stage III-IV DLBCL patients treated was conducted. The iPET scan was performed after 4 cycles of RCHOP (rituximab 375 mg/m2 d1; cyclophosphamide 750 mg/m2 d2; doxorubicin 50 mg/m2 d2; vincristine 1.4 mg/m2 [maximum 2 mg] d2; prednisone 100 mg orally daily d2-6) in al… Show more

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