Interim results from a cluster randomized controlled oral cancer screening trial in Kerala, India

Ramadas, Kunnambath; Sankaranarayanan, Rengaswamy; Jacob, Binu; Thomas, Gigi; Somanathan, Thara; Mahé, Cédric; Pandey, Manoj; Abraham, Elizabeth; Najeeb, Shariq; Mathew, Babu; Parkin, Donald Maxwell; Nair, Manjusha

doi:10.1016/s1368-8375(03)00041-1

Cited by 75 publications

(63 citation statements)

References 10 publications

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“…None of the studies identified in this review reported that measure. However, 88 These latest results compare population-based mortality between the intervention and control arms of the trial, but are currently unable to demonstrate any significant difference between the groups.…”

Section: Discussionmentioning

confidence: 99%

The cost-effectiveness of screening for oral cancer in primary care

Speight

Palmer²,

Dr³

et al. 2006

Health Technol Assess

165

162

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Section: Discussionmentioning

confidence: 99%

The cost-effectiveness of screening for oral cancer in primary care

Speight

Palmer²,

Dr³

et al. 2006

Health Technol Assess

165

162

View full text Add to dashboard Cite

show abstract

“…The potential benefits of screening which include down-staging, improved survival, reassurance (for those screened negative) and decrease cost of treatment are well-established (Rodrigues et al, 1998). A community-based randomised controlled intervention trial to evaluate the efficacy of organised oral cancer screening and intervention programme in India demonstrated that multiple rounds of screening was effective in down-staging tumours and reducing oral cancer mortality particularly amongst individuals who are at high risk (Ramadas et al, 2003;Sankaranarayanan et al, 2005;2013;Brocklehurst et al, 2010). However, this was the only randomised controlled trial in the literature and therefore the real benefits and cost-effectiveness of oral cancer screening remains controversial as other studies reported high rates of false positive referrals and a low yield of oral cancer in the screened population, underlining that there is currently no definitive evidence that public screening of asymptomatic patients can reduced mortality from oral cancer (Kujan et al, 2006b).…”

mentioning

confidence: 99%

Dentists' Perception of the Role they Play in Early Detection of Oral Cancer

Saleh

Kong²,

Vengu³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: Dentists are typically the first professionals who are approached to treat ailments within the oral cavity. Therefore they should be well-equipped in detecting suspicious lesions during routine clinical practice. This study determined the levels of knowledge on early signs and risk factors associated with oral cancer and identified which factors influenced dentist participation in prevention and early detection of oral cancer. Materials and Methods: A survey on dentists' knowledge and their practices in prevention and early detection of oral cancer was conducted using a 26-item self-administered questionnaire. Results and Conclusions: A response rate of 41.7% was achieved. The level of knowledge on early signs and risk habits associated with oral cancer was high and the majority reported to have conducted opportunistic screening and advised patients on risk habit cessation. Factors that influenced the dentist in practising prevention and early detection of oral cancer were continuous education on oral cancer, age, nature of practice and recent graduation. Notably, dentists were receptive to further training in the area of oral cancer detection and cessation of risk habits. Taken together, the study demonstrated that the dental clinic is a good avenue to conduct programs on opportunistic screening, and continuous education in these areas is necessary to adequately equip dentists in running these programs. Further, this study also highlighted knowledge deficits and practice shortcomings which will help in planning and developing programs that further encourage better participation of dentists in prevention and early detection of oral cancer.

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“…What was evident in the literature reports on OSCC was the absence of standardized guidelines of oral mucosa examination that are universally practiced. There is however a consensus that routine screenings were effective at 60% sensitivity and 90% specificity and most importantly that visual inspection is very effective [22][23][24]. It appears that the current knowledge and training in oral cancer prevention and early detection among HCPs in Saudi Arabia is not up to the desired level.…”

Section: Discussionmentioning

confidence: 99%

Perception of Healthcare Practitioners of the Importance of Routine Oral-Cancer Screening

Hasanin¹

2015

JDHODT

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Introduction: In recent times, both the incidence of and death rate from oral cancers (OC) have decreased significantly due to preventive measures, early detection techniques and enhanced knowledge of clinical signs and symptoms of the disease. Oral cancer is the 11 th most common cancer in the world with approximately 389,000 new cases per year. In Saudi Arabia, it is the 3 rd most diagnosed malignancy. A direct relationship between tobacco use and oral cancer has been established. The Saudi smoker population has been observed to consume over 80 million cigarettes annually. Smoking among the Saudi general population has reached 52.3%, which makes Saudi smokers high-risk patients of oral cancer. As tumors of the oral cavity arise on an accessible and partially visible epithelial surface, they should, in principle, be diagnosed early. However, many of these tumors are diagnosed only when they are at an advanced TNM stage, typically in late terminal stages.

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Interim results from a cluster randomized controlled oral cancer screening trial in Kerala, India

Cited by 75 publications

References 10 publications

The cost-effectiveness of screening for oral cancer in primary care

The cost-effectiveness of screening for oral cancer in primary care

Dentists' Perception of the Role they Play in Early Detection of Oral Cancer

Perception of Healthcare Practitioners of the Importance of Routine Oral-Cancer Screening

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